Decreased Kidney Function of Unknown Cause in Nicaragua: A Community-Based Survey

Background End-stage kidney disease overwhelms health services in Central America. We determined prevalences of decreased kidney function in distinct populations in the most affected region of Nicaragua. Study Design Cross-sectional survey. Setting & Participants Total populations aged 20-60 yea...

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Veröffentlicht in:American journal of kidney diseases 2010-03, Vol.55 (3), p.485-496
Hauptverfasser: Torres, Cecilia, MD, Aragón, Aurora, PhD, González, Marvin, MSc, López, Indiana, PhD, Jakobsson, Kristina, PhD, Elinder, Carl-Gustaf, PhD, Lundberg, Ingvar, PhD, Wesseling, Catharina, PhD
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Sprache:eng
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Zusammenfassung:Background End-stage kidney disease overwhelms health services in Central America. We determined prevalences of decreased kidney function in distinct populations in the most affected region of Nicaragua. Study Design Cross-sectional survey. Setting & Participants Total populations aged 20-60 years of 5 villages in Northwest Nicaragua: mining/subsistence farming (elevation, 100-300 m above sea level), banana/sugarcane (100-300 m), fishing (0-100 m), services (0-100 m), and coffee (200-675 m); 479 men and 617 women (83% response). Predictor or Factor Village; participant sex, age, and occupation; conventional chronic kidney disease risk factors. Outcomes Serum creatinine (SCr) values greater than laboratory reference range for sex, estimated glomerular filtration rate 300 mg/dL) range. Results Prevalences of abnormal SCr levels: 18% (of all men) and 5% (of all women); in the mining/subsistence farming village, 26% and 7%; banana/sugarcane, 22% and 6%; fishing, 13% and 4%; services, 0% and 1%; and coffee, 7% and 0%. Prevalences of estimated glomerular filtration rate
ISSN:0272-6386
1523-6838
1523-6838
DOI:10.1053/j.ajkd.2009.12.012