Flexible Substrate-Based Devices for Point-of-Care Diagnostics

Point-of-care (POC) diagnostics play an important role in delivering healthcare, particularly for clinical management and disease surveillance in both developed and developing countries. Currently, the majority of POC diagnostics utilize paper substrates owing to affordability, disposability, and ma...

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Veröffentlicht in:Trends in biotechnology (Regular ed.) 2016-11, Vol.34 (11), p.909-921
Hauptverfasser: Wang, ShuQi, Chinnasamy, Thiruppathiraja, Lifson, Mark A, Inci, Fatih, Demirci, Utkan
Format: Artikel
Sprache:eng
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Zusammenfassung:Point-of-care (POC) diagnostics play an important role in delivering healthcare, particularly for clinical management and disease surveillance in both developed and developing countries. Currently, the majority of POC diagnostics utilize paper substrates owing to affordability, disposability, and mass production capability. Recently, flexible polymer substrates have been investigated due to their enhanced physicochemical properties, potential to be integrated into wearable devices with wireless communications for personalized health monitoring, and ability to be customized for POC diagnostics. Here, we focus on the latest advances in developing flexible substrate-based diagnostic devices, including paper and polymers, and their clinical applications.
ISSN:0167-7799
1879-3096
DOI:10.1016/j.tibtech.2016.05.009