Flexible Substrate-Based Devices for Point-of-Care Diagnostics
Point-of-care (POC) diagnostics play an important role in delivering healthcare, particularly for clinical management and disease surveillance in both developed and developing countries. Currently, the majority of POC diagnostics utilize paper substrates owing to affordability, disposability, and ma...
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| Veröffentlicht in: | Trends in biotechnology (Regular ed.) 2016-11, Vol.34 (11), p.909-921 |
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| container_title | Trends in biotechnology (Regular ed.) |
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| creator | Wang, ShuQi Chinnasamy, Thiruppathiraja Lifson, Mark A Inci, Fatih Demirci, Utkan |
| description | Point-of-care (POC) diagnostics play an important role in delivering healthcare, particularly for clinical management and disease surveillance in both developed and developing countries. Currently, the majority of POC diagnostics utilize paper substrates owing to affordability, disposability, and mass production capability. Recently, flexible polymer substrates have been investigated due to their enhanced physicochemical properties, potential to be integrated into wearable devices with wireless communications for personalized health monitoring, and ability to be customized for POC diagnostics. Here, we focus on the latest advances in developing flexible substrate-based diagnostic devices, including paper and polymers, and their clinical applications. |
| doi_str_mv | 10.1016/j.tibtech.2016.05.009 |
| format | Article |
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Currently, the majority of POC diagnostics utilize paper substrates owing to affordability, disposability, and mass production capability. Recently, flexible polymer substrates have been investigated due to their enhanced physicochemical properties, potential to be integrated into wearable devices with wireless communications for personalized health monitoring, and ability to be customized for POC diagnostics. Here, we focus on the latest advances in developing flexible substrate-based diagnostic devices, including paper and polymers, and their clinical applications.</description><identifier>ISSN: 0167-7799</identifier><identifier>EISSN: 1879-3096</identifier><identifier>DOI: 10.1016/j.tibtech.2016.05.009</identifier><identifier>PMID: 27344425</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>affordability ; Developing countries ; diagnostic techniques ; disease surveillance ; flexible substrate ; Glucose ; health services ; Heat conductivity ; Humans ; Immunoglobulins ; Internal Medicine ; Lab-On-A-Chip Devices ; Laboratories ; LDCs ; Microfluidic Analytical Techniques - instrumentation ; Monitoring, Physiologic - instrumentation ; Physicochemical properties ; Plasma etching ; Pliability ; point-of-care diagnostics ; Point-of-Care Systems ; Polyethylene terephthalate ; polymer ; Polymers ; Spectrum analysis ; Substrates ; Textiles ; Uric acid ; Urine ; wearable devices</subject><ispartof>Trends in biotechnology (Regular ed.), 2016-11, Vol.34 (11), p.909-921</ispartof><rights>Elsevier Ltd</rights><rights>2016 Elsevier Ltd</rights><rights>Copyright © 2016 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Nov 01, 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c620t-b5bddbe3059fc9e4a14e35ec12b381da05fe1a88e4350769bd96f413b4d6f5203</citedby><cites>FETCH-LOGICAL-c620t-b5bddbe3059fc9e4a14e35ec12b381da05fe1a88e4350769bd96f413b4d6f5203</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0167779916300555$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27344425$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, ShuQi</creatorcontrib><creatorcontrib>Chinnasamy, Thiruppathiraja</creatorcontrib><creatorcontrib>Lifson, Mark A</creatorcontrib><creatorcontrib>Inci, Fatih</creatorcontrib><creatorcontrib>Demirci, Utkan</creatorcontrib><title>Flexible Substrate-Based Devices for Point-of-Care Diagnostics</title><title>Trends in biotechnology (Regular ed.)</title><addtitle>Trends Biotechnol</addtitle><description>Point-of-care (POC) diagnostics play an important role in delivering healthcare, particularly for clinical management and disease surveillance in both developed and developing countries. Currently, the majority of POC diagnostics utilize paper substrates owing to affordability, disposability, and mass production capability. Recently, flexible polymer substrates have been investigated due to their enhanced physicochemical properties, potential to be integrated into wearable devices with wireless communications for personalized health monitoring, and ability to be customized for POC diagnostics. Here, we focus on the latest advances in developing flexible substrate-based diagnostic devices, including paper and polymers, and their clinical applications.</description><subject>affordability</subject><subject>Developing countries</subject><subject>diagnostic techniques</subject><subject>disease surveillance</subject><subject>flexible substrate</subject><subject>Glucose</subject><subject>health services</subject><subject>Heat conductivity</subject><subject>Humans</subject><subject>Immunoglobulins</subject><subject>Internal Medicine</subject><subject>Lab-On-A-Chip Devices</subject><subject>Laboratories</subject><subject>LDCs</subject><subject>Microfluidic Analytical Techniques - instrumentation</subject><subject>Monitoring, Physiologic - instrumentation</subject><subject>Physicochemical properties</subject><subject>Plasma etching</subject><subject>Pliability</subject><subject>point-of-care diagnostics</subject><subject>Point-of-Care Systems</subject><subject>Polyethylene terephthalate</subject><subject>polymer</subject><subject>Polymers</subject><subject>Spectrum analysis</subject><subject>Substrates</subject><subject>Textiles</subject><subject>Uric acid</subject><subject>Urine</subject><subject>wearable 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| subjects | affordability Developing countries diagnostic techniques disease surveillance flexible substrate Glucose health services Heat conductivity Humans Immunoglobulins Internal Medicine Lab-On-A-Chip Devices Laboratories LDCs Microfluidic Analytical Techniques - instrumentation Monitoring, Physiologic - instrumentation Physicochemical properties Plasma etching Pliability point-of-care diagnostics Point-of-Care Systems Polyethylene terephthalate polymer Polymers Spectrum analysis Substrates Textiles Uric acid Urine wearable devices |
| title | Flexible Substrate-Based Devices for Point-of-Care Diagnostics |
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