Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors
Human embryonic stem cells (hESCs) are self‐renewing pluripotent cells that have the capacity to differentiate into a wide variety of cell types. This potentiality represents a promising source to overcome many human diseases by providing an unlimited supply of all cell types, including cells with n...
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Veröffentlicht in: | Stem cells (Dayton, Ohio) Ohio), 2009-01, Vol.27 (1), p.78-87 |
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creator | Erceg, Slaven Ronaghi, Mohammad Stojković, Miodrag |
description | Human embryonic stem cells (hESCs) are self‐renewing pluripotent cells that have the capacity to differentiate into a wide variety of cell types. This potentiality represents a promising source to overcome many human diseases by providing an unlimited supply of all cell types, including cells with neural characteristics. Therefore, this review summarizes early neural development and the potential of hESCs to differentiate under in vitro conditions, examining at the same time the potential use of differentiated hESCs for therapeutic applications for neural tissue and cell regeneration. STEM CELLS 2009;27:78–87 |
doi_str_mv | 10.1634/stemcells.2008-0543 |
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source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Cell culture Cell Differentiation Cellular therapy Embryonic Stem Cells - cytology Embryonic Stem Cells/Induced Pluripotent Stem Cells Human embryonic stem cells Humans Neural differentiation Neurons - cytology Oligodendroglia - cytology Organ Specificity |
title | Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors |
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