Carotid artery atherosclerosis in hypertensive patients with a functional LDL receptor-related protein 6 gene variant
Abstract Background and aims Rare (611C) and common (1062V) variants of the Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6) display reduced activation of Wnt/ß-catenin signaling. The rare gene variant was associated with hypertension, metabolic abnormalities, and early coronary artery dise...
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Veröffentlicht in: | Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2011-02, Vol.21 (2), p.150-156 |
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