Carotid artery atherosclerosis in hypertensive patients with a functional LDL receptor-related protein 6 gene variant

Abstract Background and aims Rare (611C) and common (1062V) variants of the Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6) display reduced activation of Wnt/ß-catenin signaling. The rare gene variant was associated with hypertension, metabolic abnormalities, and early coronary artery dise...

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Veröffentlicht in:Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2011-02, Vol.21 (2), p.150-156
Hauptverfasser: Sarzani, R, Salvi, F, Bordicchia, M, Guerra, F, Battistoni, I, Pagliariccio, G, Carbonari, L, Dessì-Fulgheri, P, Rappelli, A
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