Preservation of canine hearts

Canine hearts were perfused for 24 hrs by hypothermic perfusion. When these hearts were resuscitated they demonstrated pressure-volume curves that were similar to their own control. Electron micrographic studies showed good morphological preservation. However, physiological preservation was not atta...

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Veröffentlicht in:Cryobiology 1970-05, Vol.6 (6), p.515-521
Hauptverfasser: Trunkey, Donald, Degenhardt, Thomas, Chartrand, Claude, Pryor, John P., Belzer, Folkert O.
Format: Artikel
Sprache:eng
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Zusammenfassung:Canine hearts were perfused for 24 hrs by hypothermic perfusion. When these hearts were resuscitated they demonstrated pressure-volume curves that were similar to their own control. Electron micrographic studies showed good morphological preservation. However, physiological preservation was not attained, as the orthotopic homotransplanted, preserved heart failed soon after orthotopic implantation.
ISSN:0011-2240
1090-2392
DOI:10.1016/S0011-2240(70)80002-5