Preservation of canine hearts

Canine hearts were perfused for 24 hrs by hypothermic perfusion. When these hearts were resuscitated they demonstrated pressure-volume curves that were similar to their own control. Electron micrographic studies showed good morphological preservation. However, physiological preservation was not atta...

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Veröffentlicht in:Cryobiology 1970-05, Vol.6 (6), p.515-521
Hauptverfasser: Trunkey, Donald, Degenhardt, Thomas, Chartrand, Claude, Pryor, John P., Belzer, Folkert O.
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container_end_page 521
container_issue 6
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container_title Cryobiology
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creator Trunkey, Donald
Degenhardt, Thomas
Chartrand, Claude
Pryor, John P.
Belzer, Folkert O.
description Canine hearts were perfused for 24 hrs by hypothermic perfusion. When these hearts were resuscitated they demonstrated pressure-volume curves that were similar to their own control. Electron micrographic studies showed good morphological preservation. However, physiological preservation was not attained, as the orthotopic homotransplanted, preserved heart failed soon after orthotopic implantation.
doi_str_mv 10.1016/S0011-2240(70)80002-5
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Animals
Dogs
Freezing
Heart - physiology
Heart Transplantation
Methods
Microscopy, Electron
Myocardium - pathology
Organ Size
Perfusion
Time Factors
Tissue Preservation
Transplantation, Homologous
title Preservation of canine hearts
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