Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study
Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was obser...
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Veröffentlicht in: | Rheumatology international 1989-07, Vol.9 (1), p.13-18 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was observed. Additional findings were a significantly increased frequency of HLA-B13 and a significant decrease of HLA-B44. |
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ISSN: | 0172-8172 1437-160X |
DOI: | 10.1007/BF00270284 |