Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study
Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was obser...
Gespeichert in:
| Veröffentlicht in: | Rheumatology international 1989-07, Vol.9 (1), p.13-18 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 18 |
|---|---|
| container_issue | 1 |
| container_start_page | 13 |
| container_title | Rheumatology international |
| container_volume | 9 |
| creator | Hartung, K Fontana, A Klar, M Krippner, H Jörgens, K Lang, B Peter, H H Pichler, W J Schendel, D Robin-Winn, M |
| description | Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was observed. Additional findings were a significantly increased frequency of HLA-B13 and a significant decrease of HLA-B44. |
| doi_str_mv | 10.1007/BF00270284 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79192040</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79192040</sourcerecordid><originalsourceid>FETCH-LOGICAL-c156t-b131adb677bd4a0e190fd8ce7639721d2e9663e2431c0a19227ac756ee6215893</originalsourceid><addsrcrecordid>eNpFkE1LAzEQhoMotX5cvAs5eRC3TrK7ye5Ri9qCIoiCtyXNTu3KftRMgvQf-LONWPQwM8zMMy_My9iJgIkA0JfXtwBSgyyyHTYWWaoToeB1l41BaJkUMe2zA6J3iL1SMGIjmUOeqmLMvq6IBtsY3ww9H5bctoaIzy_4PIbp61jn_GE25W_YI1-7oQ7WE_9s_IrThjx2jeVtWAfi6DZ-hZ3xAwWa8Cek0EY0iho-xd470_Kb4IY1mp53cdfYOEXHyYd6c8T2lqYlPN7WQ_Zye_M8nSX3j3fz6dV9YkWufLIQqTD1Qmm9qDMDKEpY1oVFrdJSS1FLLJVKUWapsGBEKaU2VucKUUmRF2V6yM5-deMvHwHJV11DFtvW9DgEqnQZjyCDCJ7_gtYNRA6X1do1nXGbSkD1Y3v1b3uET7eqYdFh_YdufU6_AS0HfOo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79192040</pqid></control><display><type>article</type><title>Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Hartung, K ; Fontana, A ; Klar, M ; Krippner, H ; Jörgens, K ; Lang, B ; Peter, H H ; Pichler, W J ; Schendel, D ; Robin-Winn, M</creator><creatorcontrib>Hartung, K ; Fontana, A ; Klar, M ; Krippner, H ; Jörgens, K ; Lang, B ; Peter, H H ; Pichler, W J ; Schendel, D ; Robin-Winn, M</creatorcontrib><description>Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was observed. Additional findings were a significantly increased frequency of HLA-B13 and a significant decrease of HLA-B44.</description><identifier>ISSN: 0172-8172</identifier><identifier>EISSN: 1437-160X</identifier><identifier>DOI: 10.1007/BF00270284</identifier><identifier>PMID: 2505368</identifier><language>eng</language><publisher>Germany</publisher><subject>Alleles ; Europe ; Gene Frequency ; Genes, MHC Class I ; Genes, MHC Class II ; HLA Antigens - analysis ; HLA Antigens - genetics ; Humans ; Lupus Erythematosus, Systemic - genetics ; Lupus Erythematosus, Systemic - immunology ; Major Histocompatibility Complex ; Multicenter Studies as Topic</subject><ispartof>Rheumatology international, 1989-07, Vol.9 (1), p.13-18</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c156t-b131adb677bd4a0e190fd8ce7639721d2e9663e2431c0a19227ac756ee6215893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2505368$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hartung, K</creatorcontrib><creatorcontrib>Fontana, A</creatorcontrib><creatorcontrib>Klar, M</creatorcontrib><creatorcontrib>Krippner, H</creatorcontrib><creatorcontrib>Jörgens, K</creatorcontrib><creatorcontrib>Lang, B</creatorcontrib><creatorcontrib>Peter, H H</creatorcontrib><creatorcontrib>Pichler, W J</creatorcontrib><creatorcontrib>Schendel, D</creatorcontrib><creatorcontrib>Robin-Winn, M</creatorcontrib><title>Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study</title><title>Rheumatology international</title><addtitle>Rheumatol Int</addtitle><description>Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was observed. Additional findings were a significantly increased frequency of HLA-B13 and a significant decrease of HLA-B44.</description><subject>Alleles</subject><subject>Europe</subject><subject>Gene Frequency</subject><subject>Genes, MHC Class I</subject><subject>Genes, MHC Class II</subject><subject>HLA Antigens - analysis</subject><subject>HLA Antigens - genetics</subject><subject>Humans</subject><subject>Lupus Erythematosus, Systemic - genetics</subject><subject>Lupus Erythematosus, Systemic - immunology</subject><subject>Major Histocompatibility Complex</subject><subject>Multicenter Studies as Topic</subject><issn>0172-8172</issn><issn>1437-160X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LAzEQhoMotX5cvAs5eRC3TrK7ye5Ri9qCIoiCtyXNTu3KftRMgvQf-LONWPQwM8zMMy_My9iJgIkA0JfXtwBSgyyyHTYWWaoToeB1l41BaJkUMe2zA6J3iL1SMGIjmUOeqmLMvq6IBtsY3ww9H5bctoaIzy_4PIbp61jn_GE25W_YI1-7oQ7WE_9s_IrThjx2jeVtWAfi6DZ-hZ3xAwWa8Cek0EY0iho-xd470_Kb4IY1mp53cdfYOEXHyYd6c8T2lqYlPN7WQ_Zye_M8nSX3j3fz6dV9YkWufLIQqTD1Qmm9qDMDKEpY1oVFrdJSS1FLLJVKUWapsGBEKaU2VucKUUmRF2V6yM5-deMvHwHJV11DFtvW9DgEqnQZjyCDCJ7_gtYNRA6X1do1nXGbSkD1Y3v1b3uET7eqYdFh_YdufU6_AS0HfOo</recordid><startdate>198907</startdate><enddate>198907</enddate><creator>Hartung, K</creator><creator>Fontana, A</creator><creator>Klar, M</creator><creator>Krippner, H</creator><creator>Jörgens, K</creator><creator>Lang, B</creator><creator>Peter, H H</creator><creator>Pichler, W J</creator><creator>Schendel, D</creator><creator>Robin-Winn, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198907</creationdate><title>Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study</title><author>Hartung, K ; Fontana, A ; Klar, M ; Krippner, H ; Jörgens, K ; Lang, B ; Peter, H H ; Pichler, W J ; Schendel, D ; Robin-Winn, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c156t-b131adb677bd4a0e190fd8ce7639721d2e9663e2431c0a19227ac756ee6215893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Alleles</topic><topic>Europe</topic><topic>Gene Frequency</topic><topic>Genes, MHC Class I</topic><topic>Genes, MHC Class II</topic><topic>HLA Antigens - analysis</topic><topic>HLA Antigens - genetics</topic><topic>Humans</topic><topic>Lupus Erythematosus, Systemic - genetics</topic><topic>Lupus Erythematosus, Systemic - immunology</topic><topic>Major Histocompatibility Complex</topic><topic>Multicenter Studies as Topic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hartung, K</creatorcontrib><creatorcontrib>Fontana, A</creatorcontrib><creatorcontrib>Klar, M</creatorcontrib><creatorcontrib>Krippner, H</creatorcontrib><creatorcontrib>Jörgens, K</creatorcontrib><creatorcontrib>Lang, B</creatorcontrib><creatorcontrib>Peter, H H</creatorcontrib><creatorcontrib>Pichler, W J</creatorcontrib><creatorcontrib>Schendel, D</creatorcontrib><creatorcontrib>Robin-Winn, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Rheumatology international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hartung, K</au><au>Fontana, A</au><au>Klar, M</au><au>Krippner, H</au><au>Jörgens, K</au><au>Lang, B</au><au>Peter, H H</au><au>Pichler, W J</au><au>Schendel, D</au><au>Robin-Winn, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study</atitle><jtitle>Rheumatology international</jtitle><addtitle>Rheumatol Int</addtitle><date>1989-07</date><risdate>1989</risdate><volume>9</volume><issue>1</issue><spage>13</spage><epage>18</epage><pages>13-18</pages><issn>0172-8172</issn><eissn>1437-160X</eissn><abstract>Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was observed. Additional findings were a significantly increased frequency of HLA-B13 and a significant decrease of HLA-B44.</abstract><cop>Germany</cop><pmid>2505368</pmid><doi>10.1007/BF00270284</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0172-8172 |
| ispartof | Rheumatology international, 1989-07, Vol.9 (1), p.13-18 |
| issn | 0172-8172 1437-160X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79192040 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Alleles Europe Gene Frequency Genes, MHC Class I Genes, MHC Class II HLA Antigens - analysis HLA Antigens - genetics Humans Lupus Erythematosus, Systemic - genetics Lupus Erythematosus, Systemic - immunology Major Histocompatibility Complex Multicenter Studies as Topic |
| title | Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-20T11%3A48%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Association%20of%20class%20I,%20II,%20and%20III%20MHC%20gene%20products%20with%20systemic%20lupus%20erythematosus.%20Results%20of%20a%20Central%20European%20multicenter%20study&rft.jtitle=Rheumatology%20international&rft.au=Hartung,%20K&rft.date=1989-07&rft.volume=9&rft.issue=1&rft.spage=13&rft.epage=18&rft.pages=13-18&rft.issn=0172-8172&rft.eissn=1437-160X&rft_id=info:doi/10.1007/BF00270284&rft_dat=%3Cproquest_cross%3E79192040%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79192040&rft_id=info:pmid/2505368&rfr_iscdi=true |