X‐Ray, NMR, and Theoretical Studies of the Nootropic Agent BMY‐21502, a Pyrrolidinone Derivative
The preferred crystalline, solution, andin vacuoarrangements of 1‐[[1‐[2‐(trifluoromethyl)‐4‐pyrimidinyl]‐4‐piperidinyl]methyl]‐2‐pyrrolidinone (BMY‐21502) were investigated by means of single‐crystal X‐ray diffraction,1H and13C NMR spectroscopy, and semiempirical molecular orbital and molecular mec...
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Veröffentlicht in: | Journal of pharmaceutical sciences 1994-06, Vol.83 (6), p.878-882 |
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Hauptverfasser: | , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | The preferred crystalline, solution, andin vacuoarrangements of 1‐[[1‐[2‐(trifluoromethyl)‐4‐pyrimidinyl]‐4‐piperidinyl]methyl]‐2‐pyrrolidinone (BMY‐21502) were investigated by means of single‐crystal X‐ray diffraction,1H and13C NMR spectroscopy, and semiempirical molecular orbital and molecular mechanics calculations. The X‐ray powder diffraction pattern is also reported. |
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ISSN: | 0022-3549 1520-6017 |
DOI: | 10.1002/jps.2600830624 |