X‐Ray, NMR, and Theoretical Studies of the Nootropic Agent BMY‐21502, a Pyrrolidinone Derivative
The preferred crystalline, solution, andin vacuoarrangements of 1‐[[1‐[2‐(trifluoromethyl)‐4‐pyrimidinyl]‐4‐piperidinyl]methyl]‐2‐pyrrolidinone (BMY‐21502) were investigated by means of single‐crystal X‐ray diffraction,1H and13C NMR spectroscopy, and semiempirical molecular orbital and molecular mec...
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| Veröffentlicht in: | Journal of pharmaceutical sciences 1994-06, Vol.83 (6), p.878-882 |
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| container_end_page | 882 |
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| container_title | Journal of pharmaceutical sciences |
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| creator | Bandoli, Giuliano Dolmella, Alessandro Nicolini, Marino Tisato, Francesco |
| description | The preferred crystalline, solution, andin vacuoarrangements of 1‐[[1‐[2‐(trifluoromethyl)‐4‐pyrimidinyl]‐4‐piperidinyl]methyl]‐2‐pyrrolidinone (BMY‐21502) were investigated by means of single‐crystal X‐ray diffraction,1H and13C NMR spectroscopy, and semiempirical molecular orbital and molecular mechanics calculations. The X‐ray powder diffraction pattern is also reported. |
| doi_str_mv | 10.1002/jps.2600830624 |
| format | Article |
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Drug treatments</topic><topic>Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)</topic><topic>Psychology. Psychoanalysis. 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| fulltext | fulltext |
| identifier | ISSN: 0022-3549 |
| ispartof | Journal of pharmaceutical sciences, 1994-06, Vol.83 (6), p.878-882 |
| issn | 0022-3549 1520-6017 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | Biological and medical sciences Magnetic Resonance Spectroscopy Medical sciences Molecular Conformation Neuropharmacology Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Psychotropic Drugs - chemistry Pyrimidines - chemistry Pyrrolidinones - chemistry X-Ray Diffraction |
| title | X‐Ray, NMR, and Theoretical Studies of the Nootropic Agent BMY‐21502, a Pyrrolidinone Derivative |
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