Heart and Lung Transplants from HCV-Infected Donors

To the Editor: Woolley et al. (April 25 issue) 1 report encouraging results of the Donors of Hepatitis C NAT [nucleic acid amplification test] Positive Thoracic Allografts for Transplantation Evaluation in Non-HCV Recipients (DONATE HCV) trial, which showed safety and efficacy of preemptive direct-a...

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Veröffentlicht in:The New England journal of medicine 2019-09, Vol.381 (10), p.987-989
Hauptverfasser: Elfeki, Mohamed A, Romero-Marrero, Carlos, Carey, William D, Indolfi, Giuseppe, Azzari, Chiara, Resti, Massimo, Nitta, Daisuke, Imamura, Teruhiko, Woolley, Ann E, Fanikos, John, Baden, Lindsey R
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Sprache:eng
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Zusammenfassung:To the Editor: Woolley et al. (April 25 issue) 1 report encouraging results of the Donors of Hepatitis C NAT [nucleic acid amplification test] Positive Thoracic Allografts for Transplantation Evaluation in Non-HCV Recipients (DONATE HCV) trial, which showed safety and efficacy of preemptive direct-acting antiviral therapy immediately after transplantation to treat hepatitis C virus (HCV)–negative lung-transplant and heart-transplant recipients who received grafts from donors with hepatitis C viremia. In the accompanying editorial, 2 there was concern regarding assurance of access to direct-acting antiviral therapy in advance of acceptance of a heart or lung from donors with hepatitis C viremia. Patients with Medicare . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc1907009