Heart and Lung Transplants from HCV-Infected Donors
To the Editor: Woolley et al. (April 25 issue) 1 report encouraging results of the Donors of Hepatitis C NAT [nucleic acid amplification test] Positive Thoracic Allografts for Transplantation Evaluation in Non-HCV Recipients (DONATE HCV) trial, which showed safety and efficacy of preemptive direct-a...
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Veröffentlicht in: | The New England journal of medicine 2019-09, Vol.381 (10), p.987-989 |
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container_title | The New England journal of medicine |
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creator | Elfeki, Mohamed A Romero-Marrero, Carlos Carey, William D Indolfi, Giuseppe Azzari, Chiara Resti, Massimo Nitta, Daisuke Imamura, Teruhiko Woolley, Ann E Fanikos, John Baden, Lindsey R |
description | To the Editor:
Woolley et al. (April 25 issue)
1
report encouraging results of the Donors of Hepatitis C NAT [nucleic acid amplification test] Positive Thoracic Allografts for Transplantation Evaluation in Non-HCV Recipients (DONATE HCV) trial, which showed safety and efficacy of preemptive direct-acting antiviral therapy immediately after transplantation to treat hepatitis C virus (HCV)–negative lung-transplant and heart-transplant recipients who received grafts from donors with hepatitis C viremia. In the accompanying editorial,
2
there was concern regarding assurance of access to direct-acting antiviral therapy in advance of acceptance of a heart or lung from donors with hepatitis C viremia. Patients with Medicare . . . |
doi_str_mv | 10.1056/NEJMc1907009 |
format | Article |
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Woolley et al. (April 25 issue)
1
report encouraging results of the Donors of Hepatitis C NAT [nucleic acid amplification test] Positive Thoracic Allografts for Transplantation Evaluation in Non-HCV Recipients (DONATE HCV) trial, which showed safety and efficacy of preemptive direct-acting antiviral therapy immediately after transplantation to treat hepatitis C virus (HCV)–negative lung-transplant and heart-transplant recipients who received grafts from donors with hepatitis C viremia. In the accompanying editorial,
2
there was concern regarding assurance of access to direct-acting antiviral therapy in advance of acceptance of a heart or lung from donors with hepatitis C viremia. Patients with Medicare . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMc1907009</identifier><identifier>PMID: 31483975</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Allografts ; Antiviral agents ; Donors ; Heart transplantation ; Hepatitis ; Hepatitis C ; Humans ; Interferon ; Lung Transplantation ; Thorax ; Tissue Donors ; Transplants & implants ; Viremia</subject><ispartof>The New England journal of medicine, 2019-09, Vol.381 (10), p.987-989</ispartof><rights>Copyright © 2019 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c554t-102857280a09587f25d14bdaebc6338441f098dd6ccfd9f3a3ca0bcaa2d3dcc73</citedby><cites>FETCH-LOGICAL-c554t-102857280a09587f25d14bdaebc6338441f098dd6ccfd9f3a3ca0bcaa2d3dcc73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMc1907009$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2284703474?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31483975$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Elfeki, Mohamed A</creatorcontrib><creatorcontrib>Romero-Marrero, Carlos</creatorcontrib><creatorcontrib>Carey, William D</creatorcontrib><creatorcontrib>Indolfi, Giuseppe</creatorcontrib><creatorcontrib>Azzari, Chiara</creatorcontrib><creatorcontrib>Resti, Massimo</creatorcontrib><creatorcontrib>Nitta, Daisuke</creatorcontrib><creatorcontrib>Imamura, Teruhiko</creatorcontrib><creatorcontrib>Woolley, Ann E</creatorcontrib><creatorcontrib>Fanikos, John</creatorcontrib><creatorcontrib>Baden, Lindsey R</creatorcontrib><title>Heart and Lung Transplants from HCV-Infected Donors</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Woolley et al. (April 25 issue)
1
report encouraging results of the Donors of Hepatitis C NAT [nucleic acid amplification test] Positive Thoracic Allografts for Transplantation Evaluation in Non-HCV Recipients (DONATE HCV) trial, which showed safety and efficacy of preemptive direct-acting antiviral therapy immediately after transplantation to treat hepatitis C virus (HCV)–negative lung-transplant and heart-transplant recipients who received grafts from donors with hepatitis C viremia. In the accompanying editorial,
2
there was concern regarding assurance of access to direct-acting antiviral therapy in advance of acceptance of a heart or lung from donors with hepatitis C viremia. Patients with Medicare . . .</description><subject>Allografts</subject><subject>Antiviral agents</subject><subject>Donors</subject><subject>Heart transplantation</subject><subject>Hepatitis</subject><subject>Hepatitis C</subject><subject>Humans</subject><subject>Interferon</subject><subject>Lung Transplantation</subject><subject>Thorax</subject><subject>Tissue Donors</subject><subject>Transplants & implants</subject><subject>Viremia</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0T1PwzAQBmALgWgpbMwoEgwMBM6xHccjKoUWFVgKa-T4A7VqnGInA_8eVy0IIYbe4uXR6zu9CJ1iuMbA8pvn0eOTwgI4gNhDfcwISSmFfB_1AbIipVyQHjoKYQFxMBWHqEcwLYjgrI_I2EjfJtLpZNq592TmpQurpXRtSKxv6mQ8fEsnzhrVGp3cNa7x4RgdWLkM5mT7DtDr_Wg2HKfTl4fJ8HaaKsZom-L4O-NZARIEK7jNmMa00tJUKiekoBRbEIXWuVJWC0skURIqJWWmiVaKkwG63OSufPPRmdCW9Twos4zbmaYLZRbzMdB41I40YyTflRJY0_M_dNF03sWb14pyIJTTqK42SvkmBG9sufLzWvrPEkO5rqj8XVHkZ9vQrqqN_sHfnURwsQF1HUpnFvX_OV-xa5L4</recordid><startdate>20190905</startdate><enddate>20190905</enddate><creator>Elfeki, Mohamed A</creator><creator>Romero-Marrero, Carlos</creator><creator>Carey, William D</creator><creator>Indolfi, Giuseppe</creator><creator>Azzari, Chiara</creator><creator>Resti, Massimo</creator><creator>Nitta, Daisuke</creator><creator>Imamura, Teruhiko</creator><creator>Woolley, Ann E</creator><creator>Fanikos, John</creator><creator>Baden, Lindsey R</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20190905</creationdate><title>Heart and Lung Transplants from HCV-Infected Donors</title><author>Elfeki, Mohamed A ; Romero-Marrero, Carlos ; Carey, William D ; Indolfi, Giuseppe ; Azzari, Chiara ; Resti, Massimo ; Nitta, Daisuke ; Imamura, Teruhiko ; Woolley, Ann E ; Fanikos, John ; Baden, Lindsey R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c554t-102857280a09587f25d14bdaebc6338441f098dd6ccfd9f3a3ca0bcaa2d3dcc73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Allografts</topic><topic>Antiviral agents</topic><topic>Donors</topic><topic>Heart transplantation</topic><topic>Hepatitis</topic><topic>Hepatitis C</topic><topic>Humans</topic><topic>Interferon</topic><topic>Lung Transplantation</topic><topic>Thorax</topic><topic>Tissue Donors</topic><topic>Transplants & implants</topic><topic>Viremia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elfeki, Mohamed A</creatorcontrib><creatorcontrib>Romero-Marrero, Carlos</creatorcontrib><creatorcontrib>Carey, William D</creatorcontrib><creatorcontrib>Indolfi, Giuseppe</creatorcontrib><creatorcontrib>Azzari, Chiara</creatorcontrib><creatorcontrib>Resti, Massimo</creatorcontrib><creatorcontrib>Nitta, Daisuke</creatorcontrib><creatorcontrib>Imamura, Teruhiko</creatorcontrib><creatorcontrib>Woolley, Ann E</creatorcontrib><creatorcontrib>Fanikos, John</creatorcontrib><creatorcontrib>Baden, Lindsey R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elfeki, Mohamed A</au><au>Romero-Marrero, Carlos</au><au>Carey, William D</au><au>Indolfi, Giuseppe</au><au>Azzari, Chiara</au><au>Resti, Massimo</au><au>Nitta, Daisuke</au><au>Imamura, Teruhiko</au><au>Woolley, Ann E</au><au>Fanikos, John</au><au>Baden, Lindsey R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heart and Lung Transplants from HCV-Infected Donors</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2019-09-05</date><risdate>2019</risdate><volume>381</volume><issue>10</issue><spage>987</spage><epage>989</epage><pages>987-989</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
Woolley et al. (April 25 issue)
1
report encouraging results of the Donors of Hepatitis C NAT [nucleic acid amplification test] Positive Thoracic Allografts for Transplantation Evaluation in Non-HCV Recipients (DONATE HCV) trial, which showed safety and efficacy of preemptive direct-acting antiviral therapy immediately after transplantation to treat hepatitis C virus (HCV)–negative lung-transplant and heart-transplant recipients who received grafts from donors with hepatitis C viremia. In the accompanying editorial,
2
there was concern regarding assurance of access to direct-acting antiviral therapy in advance of acceptance of a heart or lung from donors with hepatitis C viremia. Patients with Medicare . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>31483975</pmid><doi>10.1056/NEJMc1907009</doi><tpages>3</tpages></addata></record> |
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language | eng |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
subjects | Allografts Antiviral agents Donors Heart transplantation Hepatitis Hepatitis C Humans Interferon Lung Transplantation Thorax Tissue Donors Transplants & implants Viremia |
title | Heart and Lung Transplants from HCV-Infected Donors |
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