The mRNA expression of the human 1,25-dihydroxyvitamin D3 receptor and the c-myc protooncogene in cultured human keratinocytes

The human vitamin D receptor mRNA expression in preconfluent human cultured keratinocytes was upregulated by treatment of these cells with 10(-8) M 1,25(OH)2D3 for 24 hours. Additionally, human c-myc mRNA expression was decreased in a dose dependent manner by 1,25(OH)2D3 in both preconfluent and con...

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Veröffentlicht in:In vitro cellular & developmental biology. Animal 1994-03, Vol.30A (3), p.187-191
Hauptverfasser: HANAFIN, N. M, PERSONS, K. S, HOLICK, M. F
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container_title In vitro cellular & developmental biology. Animal
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creator HANAFIN, N. M
PERSONS, K. S
HOLICK, M. F
description The human vitamin D receptor mRNA expression in preconfluent human cultured keratinocytes was upregulated by treatment of these cells with 10(-8) M 1,25(OH)2D3 for 24 hours. Additionally, human c-myc mRNA expression was decreased in a dose dependent manner by 1,25(OH)2D3 in both preconfluent and confluent cultured human keratinocytes.
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Additionally, human c-myc mRNA expression was decreased in a dose dependent manner by 1,25(OH)2D3 in both preconfluent and confluent cultured human keratinocytes.</abstract><cop>Largo, MD</cop><pub>Society for In Vitro Biology</pub><pmid>25939167</pmid><doi>10.1007/BF02631442</doi><tpages>5</tpages></addata></record>
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ispartof In vitro cellular & developmental biology. Animal, 1994-03, Vol.30A (3), p.187-191
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source MEDLINE; JSTOR; SpringerLink Journals - AutoHoldings
subjects Biological and medical sciences
Biotechnology
Calcitriol - pharmacology
Cell Proliferation - drug effects
Cells, Cultured
Dose-Response Relationship, Drug
Fundamental and applied biological sciences. Psychology
Gene expression
Gene Expression - drug effects
Genes, myc - genetics
Genetic engineering
Genetic technics
Humans
Keratinocytes - cytology
Keratinocytes - drug effects
Keratinocytes - physiology
Methods. Procedures. Technologies
Miscellaneous
Molecular and cellular biology
Molecular genetics
Receptors, Calcitriol - genetics
RNA, Messenger
Synthetic digonucleotides and genes. Sequencing
title The mRNA expression of the human 1,25-dihydroxyvitamin D3 receptor and the c-myc protooncogene in cultured human keratinocytes
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