Imbalance of circulating lymphoid cells in Q fever endocarditis
Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naïve CD8+ T lymphocytes and CD56dim natural killer cells were decreased patients whereas central me...
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Veröffentlicht in: | Pathogens and disease 2015-03, Vol.73 (2), p.1-3 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naïve CD8+ T lymphocytes and CD56dim natural killer cells were decreased patients whereas central memory CD8+ T lymphocytes were increased. It is likely that these different subsets of immune cells play a role in the immunosuppression accompanying Q fever endocarditis. |
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ISSN: | 2049-632X 2049-632X |
DOI: | 10.1093/femspd/ftu010 |