Imbalance of circulating lymphoid cells in Q fever endocarditis
Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naïve CD8+ T lymphocytes and CD56dim natural killer cells were decreased patients whereas central me...
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| Veröffentlicht in: | Pathogens and disease 2015-03, Vol.73 (2), p.1-3 |
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| container_title | Pathogens and disease |
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| creator | Ka, Mignane B. Gondois-Rey, Françoise Ghigo, Eric Raoult, Didier Olive, Daniel Mege, Jean-Louis |
| description | Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naïve CD8+ T lymphocytes and CD56dim natural killer cells were decreased patients whereas central memory CD8+ T lymphocytes were increased. It is likely that these different subsets of immune cells play a role in the immunosuppression accompanying Q fever endocarditis. |
| doi_str_mv | 10.1093/femspd/ftu010 |
| format | Article |
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In this study, we found that naïve CD8+ T lymphocytes and CD56dim natural killer cells were decreased patients whereas central memory CD8+ T lymphocytes were increased. It is likely that these different subsets of immune cells play a role in the immunosuppression accompanying Q fever endocarditis.</description><identifier>ISSN: 2049-632X</identifier><identifier>EISSN: 2049-632X</identifier><identifier>DOI: 10.1093/femspd/ftu010</identifier><identifier>PMID: 25722485</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Aged ; Aged, 80 and over ; Blood - immunology ; CD8-Positive T-Lymphocytes - immunology ; Endocarditis, Bacterial - immunology ; Female ; Humans ; Immune response ; Killer Cells, Natural - immunology ; Lymphocyte Count ; Lymphocyte Subsets - immunology ; Lymphocytes ; Male ; Middle Aged ; Q Fever - immunology</subject><ispartof>Pathogens and disease, 2015-03, Vol.73 (2), p.1-3</ispartof><rights>FEMS 2014. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com 2014</rights><rights>FEMS 2014. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><rights>Copyright Oxford University Press, UK Mar 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-759b832036c6413d24c5fa7d465502ca08a76dc9dcbc72264e7a184a82e618d53</citedby><cites>FETCH-LOGICAL-c393t-759b832036c6413d24c5fa7d465502ca08a76dc9dcbc72264e7a184a82e618d53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1598,27901,27902</link.rule.ids><linktorsrc>$$Uhttps://dx.doi.org/10.1093/femspd/ftu010$$EView_record_in_Oxford_University_Press$$FView_record_in_$$GOxford_University_Press</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25722485$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ka, Mignane B.</creatorcontrib><creatorcontrib>Gondois-Rey, Françoise</creatorcontrib><creatorcontrib>Ghigo, Eric</creatorcontrib><creatorcontrib>Raoult, Didier</creatorcontrib><creatorcontrib>Olive, Daniel</creatorcontrib><creatorcontrib>Mege, Jean-Louis</creatorcontrib><title>Imbalance of circulating lymphoid cells in Q fever endocarditis</title><title>Pathogens and disease</title><addtitle>Pathog Dis</addtitle><description>Q fever endocarditis is characterized by a defective cell-mediated immune response, which may be associated with the dysregulation of circulating subsets of immune cells. In this study, we found that naïve CD8+ T lymphocytes and CD56dim natural killer cells were decreased patients whereas central memory CD8+ T lymphocytes were increased. It is likely that these different subsets of immune cells play a role in the immunosuppression accompanying Q fever endocarditis.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Blood - immunology</subject><subject>CD8-Positive T-Lymphocytes - immunology</subject><subject>Endocarditis, Bacterial - immunology</subject><subject>Female</subject><subject>Humans</subject><subject>Immune response</subject><subject>Killer Cells, Natural - immunology</subject><subject>Lymphocyte Count</subject><subject>Lymphocyte Subsets - immunology</subject><subject>Lymphocytes</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Q Fever - immunology</subject><issn>2049-632X</issn><issn>2049-632X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkM1LwzAYh4MobswdvUrBi5e6fCc9iQw_BgMRFLyFNEm1o21q0gr77-3o_MCLubw5PPx4eAA4RfASwYwsClfH1i6KrocIHoAphjRLOcEvh7_-EzCPcQOHJxmSgh-DCWYCYyrZFFyt6lxXujEu8UViymD6Sndl85pU27p986VNjKuqmJRN8pgU7sOFxDXWGx1s2ZXxBBwVuopuvr8z8Hx787S8T9cPd6vl9To1JCNdKliWS4Ih4YZTRCymhhVaWMoZg9hoKLXg1mTW5GZQ49QJjSTVEjuOpGVkBi7G3Tb4997FTtVl3Jnpxvk-KsQFIYLRTAzo-R904_vQDHYKSZZRzPDQbgbSkTLBxxhcodpQ1jpsFYJqF1eNcdUYd-DP9qt9Xjv7TX-l_DH0ffvP1ifMOoMj</recordid><startdate>20150301</startdate><enddate>20150301</enddate><creator>Ka, Mignane B.</creator><creator>Gondois-Rey, Françoise</creator><creator>Ghigo, Eric</creator><creator>Raoult, Didier</creator><creator>Olive, Daniel</creator><creator>Mege, Jean-Louis</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T7</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>P64</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20150301</creationdate><title>Imbalance of circulating lymphoid cells in Q fever endocarditis</title><author>Ka, Mignane B. ; 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| subjects | Aged Aged, 80 and over Blood - immunology CD8-Positive T-Lymphocytes - immunology Endocarditis, Bacterial - immunology Female Humans Immune response Killer Cells, Natural - immunology Lymphocyte Count Lymphocyte Subsets - immunology Lymphocytes Male Middle Aged Q Fever - immunology |
| title | Imbalance of circulating lymphoid cells in Q fever endocarditis |
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