BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF

Provided herein are bispecific antigen-binding molecules that bind to PD-L1 and/or CD40. Further provided herein are therapeutic uses of and methods of producing such molecules and related pharmaceutical compositions, nucleic acid molecules, expression vectors and host cells. L'invention concer...

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Hauptverfasser: BIENVENUE, David, NELSON, Michelle H, FRANKE-WELCH, Secil, RAMOS, Hilario, BAILEY, Matthew J, HAGLIN, Elizabeth R, PAVLIK, Peter, MISHER, Lynda
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creator BIENVENUE, David
NELSON, Michelle H
FRANKE-WELCH, Secil
RAMOS, Hilario
BAILEY, Matthew J
HAGLIN, Elizabeth R
PAVLIK, Peter
MISHER, Lynda
description Provided herein are bispecific antigen-binding molecules that bind to PD-L1 and/or CD40. Further provided herein are therapeutic uses of and methods of producing such molecules and related pharmaceutical compositions, nucleic acid molecules, expression vectors and host cells. L'invention concerne des molécules bispécifiques de liaison à l'antigène qui se lient à PD-L1 et/ou CD40. L'invention concerne en outre des utilisations thérapeutiques et des procédés de production de telles molécules et des compositions pharmaceutiques, des molécules d'acide nucléique, des vecteurs d'expression et des cellules hôtes associés.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF
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