BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF
Provided herein are bispecific antigen-binding molecules that bind to PD-L1 and/or CD40. Further provided herein are therapeutic uses of and methods of producing such molecules and related pharmaceutical compositions, nucleic acid molecules, expression vectors and host cells. L'invention concer...
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creator | BIENVENUE, David NELSON, Michelle H FRANKE-WELCH, Secil RAMOS, Hilario BAILEY, Matthew J HAGLIN, Elizabeth R PAVLIK, Peter MISHER, Lynda |
description | Provided herein are bispecific antigen-binding molecules that bind to PD-L1 and/or CD40. Further provided herein are therapeutic uses of and methods of producing such molecules and related pharmaceutical compositions, nucleic acid molecules, expression vectors and host cells.
L'invention concerne des molécules bispécifiques de liaison à l'antigène qui se lient à PD-L1 et/ou CD40. L'invention concerne en outre des utilisations thérapeutiques et des procédés de production de telles molécules et des compositions pharmaceutiques, des molécules d'acide nucléique, des vecteurs d'expression et des cellules hôtes associés. |
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L'invention concerne des molécules bispécifiques de liaison à l'antigène qui se lient à PD-L1 et/ou CD40. L'invention concerne en outre des utilisations thérapeutiques et des procédés de production de telles molécules et des compositions pharmaceutiques, des molécules d'acide nucléique, des vecteurs d'expression et des cellules hôtes associés.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240711&DB=EPODOC&CC=WO&NR=2024148328A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240711&DB=EPODOC&CC=WO&NR=2024148328A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BIENVENUE, David</creatorcontrib><creatorcontrib>NELSON, Michelle H</creatorcontrib><creatorcontrib>FRANKE-WELCH, Secil</creatorcontrib><creatorcontrib>RAMOS, Hilario</creatorcontrib><creatorcontrib>BAILEY, Matthew J</creatorcontrib><creatorcontrib>HAGLIN, Elizabeth R</creatorcontrib><creatorcontrib>PAVLIK, Peter</creatorcontrib><creatorcontrib>MISHER, Lynda</creatorcontrib><title>BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF</title><description>Provided herein are bispecific antigen-binding molecules that bind to PD-L1 and/or CD40. Further provided herein are therapeutic uses of and methods of producing such molecules and related pharmaceutical compositions, nucleic acid molecules, expression vectors and host cells.
L'invention concerne des molécules bispécifiques de liaison à l'antigène qui se lient à PD-L1 et/ou CD40. L'invention concerne en outre des utilisations thérapeutiques et des procédés de production de telles molécules et des compositions pharmaceutiques, des molécules d'acide nucléique, des vecteurs d'expression et des cellules hôtes associés.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLBx8gwOcHX2dPN0Vghw0fUxVHD0c1FwdjExUHDy9HPx9HNX8PX3cXUO9XENBkuFBgMZIR6uQa7-bjwMrGmJOcWpvFCam0HZzTXE2UM3tSA_PrW4IDE5NS-1JD7c38jAyMTQxMLYyMLRyJg4VQA9himq</recordid><startdate>20240711</startdate><enddate>20240711</enddate><creator>BIENVENUE, David</creator><creator>NELSON, Michelle H</creator><creator>FRANKE-WELCH, Secil</creator><creator>RAMOS, Hilario</creator><creator>BAILEY, Matthew J</creator><creator>HAGLIN, Elizabeth R</creator><creator>PAVLIK, Peter</creator><creator>MISHER, Lynda</creator><scope>EVB</scope></search><sort><creationdate>20240711</creationdate><title>BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF</title><author>BIENVENUE, David ; NELSON, Michelle H ; FRANKE-WELCH, Secil ; RAMOS, Hilario ; BAILEY, Matthew J ; HAGLIN, Elizabeth R ; PAVLIK, Peter ; MISHER, Lynda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024148328A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BIENVENUE, David</creatorcontrib><creatorcontrib>NELSON, Michelle H</creatorcontrib><creatorcontrib>FRANKE-WELCH, Secil</creatorcontrib><creatorcontrib>RAMOS, Hilario</creatorcontrib><creatorcontrib>BAILEY, Matthew J</creatorcontrib><creatorcontrib>HAGLIN, Elizabeth R</creatorcontrib><creatorcontrib>PAVLIK, Peter</creatorcontrib><creatorcontrib>MISHER, Lynda</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BIENVENUE, David</au><au>NELSON, Michelle H</au><au>FRANKE-WELCH, Secil</au><au>RAMOS, Hilario</au><au>BAILEY, Matthew J</au><au>HAGLIN, Elizabeth R</au><au>PAVLIK, Peter</au><au>MISHER, Lynda</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF</title><date>2024-07-11</date><risdate>2024</risdate><abstract>Provided herein are bispecific antigen-binding molecules that bind to PD-L1 and/or CD40. Further provided herein are therapeutic uses of and methods of producing such molecules and related pharmaceutical compositions, nucleic acid molecules, expression vectors and host cells.
L'invention concerne des molécules bispécifiques de liaison à l'antigène qui se lient à PD-L1 et/ou CD40. L'invention concerne en outre des utilisations thérapeutiques et des procédés de production de telles molécules et des compositions pharmaceutiques, des molécules d'acide nucléique, des vecteurs d'expression et des cellules hôtes associés.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF |
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