BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF

BISPECIFIC PD-L1 AND CD40 BINDING MOLECULES AND USES THEREOF

Provided herein are bispecific antigen-binding molecules that bind to PD-L1 and/or CD40. Further provided herein are therapeutic uses of and methods of producing such molecules and related pharmaceutical compositions, nucleic acid molecules, expression vectors and host cells. L'invention concer...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BIENVENUE, David, NELSON, Michelle H, FRANKE-WELCH, Secil, RAMOS, Hilario, BAILEY, Matthew J, HAGLIN, Elizabeth R, PAVLIK, Peter, MISHER, Lynda
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Provided herein are bispecific antigen-binding molecules that bind to PD-L1 and/or CD40. Further provided herein are therapeutic uses of and methods of producing such molecules and related pharmaceutical compositions, nucleic acid molecules, expression vectors and host cells. L'invention concerne des molécules bispécifiques de liaison à l'antigène qui se lient à PD-L1 et/ou CD40. L'invention concerne en outre des utilisations thérapeutiques et des procédés de production de telles molécules et des compositions pharmaceutiques, des molécules d'acide nucléique, des vecteurs d'expression et des cellules hôtes associés.