FORBINDELSER TIL INHIBERING AF NOTCH-SIGNALVEJEN

The present invention provides the following compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions containing said compounds useful as a Notch pathway signaling inhibitor for the treatment of named cancers, sensorineural hearing loss caused by auditory hair cell lo...

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Bibliographische Detailangaben
Hauptverfasser: GILL, John C, HIPSKIND, Philip Arthur, EDGE, Albert, VAN ES, Helmuth Hendrikus Gerardus, CLAY, Julia Marie, PATEL, Bharvin Kumar, WROBLESKI, Aaron D, ZHAO, Gaiying
Format: Patent
Sprache:dan
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Zusammenfassung:The present invention provides the following compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions containing said compounds useful as a Notch pathway signaling inhibitor for the treatment of named cancers, sensorineural hearing loss caused by auditory hair cell loss, and inducing auditory hair cell generation.