FORBINDELSER TIL INHIBERING AF NOTCH-SIGNALVEJEN

The present invention provides the following compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions containing said compounds useful as a Notch pathway signaling inhibitor for the treatment of named cancers, sensorineural hearing loss caused by auditory hair cell lo...

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Hauptverfasser: GILL, John C, HIPSKIND, Philip Arthur, EDGE, Albert, VAN ES, Helmuth Hendrikus Gerardus, CLAY, Julia Marie, PATEL, Bharvin Kumar, WROBLESKI, Aaron D, ZHAO, Gaiying
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creator GILL, John C
HIPSKIND, Philip Arthur
EDGE, Albert
VAN ES, Helmuth Hendrikus Gerardus
CLAY, Julia Marie
PATEL, Bharvin Kumar
WROBLESKI, Aaron D
ZHAO, Gaiying
description The present invention provides the following compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions containing said compounds useful as a Notch pathway signaling inhibitor for the treatment of named cancers, sensorineural hearing loss caused by auditory hair cell loss, and inducing auditory hair cell generation.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title FORBINDELSER TIL INHIBERING AF NOTCH-SIGNALVEJEN
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