ANTIBODY DRUG CONJUGATES
The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I): La présente invention...
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creator | VYSKOCIL, STEPAN LANGSTON, STEVE P SHI, ZHAN NISHIMOTO, YUTAKA WANG, JIANING ISHII, YUMIKO MA, LITING LEE, HONG MYUNG ENGLAND, DYLAN BRADLEY XU, HE |
description | The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I):
La présente invention concerne des conjugués anticorps-médicament comprenant des modulateurs de STING. L'invention concerne également des compositions comprenant ces conjugués anticorps-médicament. Ces composés et ces compositions sont utiles pour stimuler une réponse immunitaire chez un sujet en ayant besoin. |
format | Patent |
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La présente invention concerne des conjugués anticorps-médicament comprenant des modulateurs de STING. L'invention concerne également des compositions comprenant ces conjugués anticorps-médicament. Ces composés et ces compositions sont utiles pour stimuler une réponse immunitaire chez un sujet en ayant besoin.</description><language>eng ; fre</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; DERIVATIVES THEREOF ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SUGARS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201119&DB=EPODOC&CC=CA&NR=3139809A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201119&DB=EPODOC&CC=CA&NR=3139809A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>VYSKOCIL, STEPAN</creatorcontrib><creatorcontrib>LANGSTON, STEVE P</creatorcontrib><creatorcontrib>SHI, ZHAN</creatorcontrib><creatorcontrib>NISHIMOTO, YUTAKA</creatorcontrib><creatorcontrib>WANG, JIANING</creatorcontrib><creatorcontrib>ISHII, YUMIKO</creatorcontrib><creatorcontrib>MA, LITING</creatorcontrib><creatorcontrib>LEE, HONG MYUNG</creatorcontrib><creatorcontrib>ENGLAND, DYLAN BRADLEY</creatorcontrib><creatorcontrib>XU, HE</creatorcontrib><title>ANTIBODY DRUG CONJUGATES</title><description>The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I):
La présente invention concerne des conjugués anticorps-médicament comprenant des modulateurs de STING. L'invention concerne également des compositions comprenant ces conjugués anticorps-médicament. Ces composés et ces compositions sont utiles pour stimuler une réponse immunitaire chez un sujet en ayant besoin.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJBw9AvxdPJ3iVRwCQp1V3D29_MKdXcMcQ3mYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxzo7GhsaWFgaWjobGRCgBALldH0Y</recordid><startdate>20201119</startdate><enddate>20201119</enddate><creator>VYSKOCIL, STEPAN</creator><creator>LANGSTON, STEVE P</creator><creator>SHI, ZHAN</creator><creator>NISHIMOTO, YUTAKA</creator><creator>WANG, JIANING</creator><creator>ISHII, YUMIKO</creator><creator>MA, LITING</creator><creator>LEE, HONG MYUNG</creator><creator>ENGLAND, DYLAN BRADLEY</creator><creator>XU, HE</creator><scope>EVB</scope></search><sort><creationdate>20201119</creationdate><title>ANTIBODY DRUG CONJUGATES</title><author>VYSKOCIL, STEPAN ; LANGSTON, STEVE P ; SHI, ZHAN ; NISHIMOTO, YUTAKA ; WANG, JIANING ; ISHII, YUMIKO ; MA, LITING ; LEE, HONG MYUNG ; ENGLAND, DYLAN BRADLEY ; XU, HE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3139809A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>VYSKOCIL, STEPAN</creatorcontrib><creatorcontrib>LANGSTON, STEVE P</creatorcontrib><creatorcontrib>SHI, ZHAN</creatorcontrib><creatorcontrib>NISHIMOTO, YUTAKA</creatorcontrib><creatorcontrib>WANG, JIANING</creatorcontrib><creatorcontrib>ISHII, YUMIKO</creatorcontrib><creatorcontrib>MA, LITING</creatorcontrib><creatorcontrib>LEE, HONG MYUNG</creatorcontrib><creatorcontrib>ENGLAND, DYLAN BRADLEY</creatorcontrib><creatorcontrib>XU, HE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>VYSKOCIL, STEPAN</au><au>LANGSTON, STEVE P</au><au>SHI, ZHAN</au><au>NISHIMOTO, YUTAKA</au><au>WANG, JIANING</au><au>ISHII, YUMIKO</au><au>MA, LITING</au><au>LEE, HONG MYUNG</au><au>ENGLAND, DYLAN BRADLEY</au><au>XU, HE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTIBODY DRUG CONJUGATES</title><date>2020-11-19</date><risdate>2020</risdate><abstract>The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I):
La présente invention concerne des conjugués anticorps-médicament comprenant des modulateurs de STING. L'invention concerne également des compositions comprenant ces conjugués anticorps-médicament. Ces composés et ces compositions sont utiles pour stimuler une réponse immunitaire chez un sujet en ayant besoin.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
title | ANTIBODY DRUG CONJUGATES |
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