ANTIBODY DRUG CONJUGATES

The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I): La présente invention...

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Hauptverfasser: VYSKOCIL, STEPAN, LANGSTON, STEVE P, SHI, ZHAN, NISHIMOTO, YUTAKA, WANG, JIANING, ISHII, YUMIKO, MA, LITING, LEE, HONG MYUNG, ENGLAND, DYLAN BRADLEY, XU, HE
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creator VYSKOCIL, STEPAN
LANGSTON, STEVE P
SHI, ZHAN
NISHIMOTO, YUTAKA
WANG, JIANING
ISHII, YUMIKO
MA, LITING
LEE, HONG MYUNG
ENGLAND, DYLAN BRADLEY
XU, HE
description The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I): La présente invention concerne des conjugués anticorps-médicament comprenant des modulateurs de STING. L'invention concerne également des compositions comprenant ces conjugués anticorps-médicament. Ces composés et ces compositions sont utiles pour stimuler une réponse immunitaire chez un sujet en ayant besoin.
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Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I): La présente invention concerne des conjugués anticorps-médicament comprenant des modulateurs de STING. L'invention concerne également des compositions comprenant ces conjugués anticorps-médicament. 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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
title ANTIBODY DRUG CONJUGATES
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