ANTIBODY DRUG CONJUGATES

The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I): La présente invention...

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Bibliographische Detailangaben
Hauptverfasser:	VYSKOCIL, STEPAN, LANGSTON, STEVE P, SHI, ZHAN, NISHIMOTO, YUTAKA, WANG, JIANING, ISHII, YUMIKO, MA, LITING, LEE, HONG MYUNG, ENGLAND, DYLAN BRADLEY, XU, HE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	The present disclosure provides antibody drug conjugates comprising STING modulators. Also provided are compositions comprising the antibody drug conjugates. The compounds and compositions are useful for stimulating an immune response in a subject in need thereof. Formula (I): La présente invention concerne des conjugués anticorps-médicament comprenant des modulateurs de STING. L'invention concerne également des compositions comprenant ces conjugués anticorps-médicament. Ces composés et ces compositions sont utiles pour stimuler une réponse immunitaire chez un sujet en ayant besoin.