Ethanolic Extracts of the Gongronema latifolium Stem and Leaves Caused Mild Renal Injury and Modulated Serum Triglycerides in Rats
Gongronema latifolium is a tropical plant with verse traditionally and medicinal uses in mostly Africa and Asia. In this work, we determined the biochemical effects of G. latifolium ethanolic extracts in male Wistar rats. The G. latifolium stem and leaves were air-dried separately, macerated, and ex...
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Veröffentlicht in: | Biointerface Research in Applied Chemistry 2022-08, Vol.12 (4), p.5045-5053 |
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Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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Zusammenfassung: | Gongronema latifolium is a tropical plant with verse traditionally and medicinal uses in mostly Africa and Asia. In this work, we determined the biochemical effects of G. latifolium ethanolic extracts in male Wistar rats. The G. latifolium stem and leaves were air-dried separately, macerated, and extracted in 80 % ethanol. The Wistar rats were assigned into three groups randomly; control was administered distilled water, the treatment groups respectively were given 200 mg/kg bw of the extracts of leaves or stem for twenty-eight (28) days. Data showed that the rat serum ALT and ALP activities were lower in the extract-treated group than in the control group administered distilled water. In the rat liver, there were significant differences (p |
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ISSN: | 2069-5837 2069-5837 |
DOI: | 10.33263/BRIAC124.50455053 |