Abstract 9177: Prognostic Value of Chronic Kidney Disease and Cardiac Sympathetic Dysfunction Assessed by 123I-metaiodobenzylguanidine Scintigraphy for Lethal Arrhythmic Events in Chronic Heart Failure

Abstract 9177: Prognostic Value of Chronic Kidney Disease and Cardiac Sympathetic Dysfunction Assessed by 123I-metaiodobenzylguanidine Scintigraphy for Lethal Arrhythmic Events in Chronic Heart Failure

IntroductionClinical implication of chronic kidney disease (CKD) and cardiac sympathetic nerve activity (CSNA) for lethal arrhythmic events has not been fully elucidated in patients with chronic heart failure (CHF). HypothesisThe combination of CKD and abnormal CSNA, assessed by 123I-metaiodobenzylg...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 2021-11, Vol.144 (Suppl_1), p.A9177-A9177
Hauptverfasser: Amami, Kazuaki, Yamada, Shinya, Kaneshiro, Takashi, Yoshihisa, Akiomi, Hijioka, Naoko, Nodera, Minoru, Takeishi, Yasuchika
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Sprache:eng
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Zusammenfassung:IntroductionClinical implication of chronic kidney disease (CKD) and cardiac sympathetic nerve activity (CSNA) for lethal arrhythmic events has not been fully elucidated in patients with chronic heart failure (CHF). HypothesisThe combination of CKD and abnormal CSNA, assessed by 123I-metaiodobenzylguanidine (123I-MIBG) scintigraphy, may provide useful prognostic information for the incidence of lethal arrhythmic events. MethodsWe studied 165 consecutive hospitalized CHF patients without dialysis. In a clinically stable condition, cardiac 123I-MIBG scintigraphy was performed. CKD was defined as estimated glomerular filtration rate (eGFR)
ISSN:0009-7322
DOI:10.1161/circ.144.suppl_1.9177