Abstract 14725: Angiographic Predictors of Outcome With Respect to Reperfusion Success of the Culprit Artery: CULPRIT SHOCK Angiographic Substudy

IntroductionValidation lacks for the use of the TIMI Flow Grade (TFG) and TIMI Myocardial Perfusion grade (TMP) to estimate success of a percutaneous coronary intervention in shock patients with acute myocardial infarction.HypothesisWe aimed at determining the prognostic insight of pre and post-PCI TFG and TMP in this context.MethodsCULPRIT SHOCK patients were included in the angiographic predictor analysis whenever their TFG or TMP was available in the Corelab database. A multivariable logistic regression analysis, adjusted on non-angiographic covariates, was performed to investigate if TFG or TMP separately or together, were independently associated with all-cause mortality. Results are presented as adjusted odds ratio (aOR) with 95% confidence intervals.ResultsData of 665 (96.9% of CULPRIT SHOCK study) patients were analysed. Pre-PCI TFG and TMP did not impact on mortality. When analysed in separate multivariable models, post-PCI TFG and TMP were both significantly associated with 30-day mortalityaOR 0.61 (95%CI0.38-0.97, p=0.037), and 0.46 (95%CI0.29-0.72, p