Abstract 13961: Risk Factors for Adverse Outcomes After a Glenn Procedure in Patients With a Single Ventricle

IntroductionA Glenn shunt is a low mortality operation with an uncomplicated course in most patients; however some patients can have a complicated postoperative course with significantly increased morbidity and mortality.Hypotheses1. There are potentially modifiable risk factors for a complicated Glenn (cGP, defined as someone who has died or needed heart transplant by two years of age, required extracorporeal life support (ECLS), required Glenn takedown, or needed prolonged postoperative ventilation). 2. Having a cGP predicts adverse neurodevelopmental and functional outcomes in survivors after the Glenn.MethodsA prospective Western Canadian inception-cohort of all consecutive patients having the Glenn procedure from January 2012 to December 2017. Echocardiographic, catheterization, and cardiac MRI variables were collected retrospectively. Survivors had standardized neurodevelopmental assessments at two years of age.ResultsA total of 169 patients underwent a Glenn during the study period. Twenty-seven patients (16%) met criteria for a cGPpostoperatively 8 required ECLS, 6 required Glenn takedown and 16 required prolonged ventilation (> 90 percentile; 7 days). By age 2 years, 10 patients died and 3 required transplantation. Significant predictors identified after univariate analysis (p-value