Abstract 10644: Outcomes and Determinants of Discrepant Coronary and Carotid Atherosclerosis

Background and aimsSome patients have discrepancy between carotid and coronary artery atherosclerosis. This study aimed to define the characteristics and prognosis of these discrepant patients and to determine the best strategy for detecting pan-vascular atherosclerosis.MethodsA database of 5,022 consecutively registered patients who underwent both coronary angiography and carotid ultrasonography along with clinical, blood laboratory findings, echocardiography, and pulse wave velocity (PWV) was analyzed. Developments of cerebro-cardiovascular events were also evaluated during the follow-up period.ResultsA significant proportion of patients (n=1,741, 35%) had discrepancy between carotid artery plaque and CAD. In patients without carotid plaques, male sex (odds ratio [OR], 95% confidence interval [CI]1.71 [1.20-2.41], p=0.003), older age (1.03 [1.01-1.04], p=0.002), smoking history (1.58 [1.13-2.20], p=0.008), lower high-density lipoprotein (HDL)-cholesterol level (0.97 [0.96-0.98], p