Abstract 13310: Anti-Inflammatory HDL Function and Incident Cardiovascular/Death Events: A Secondary Analysis of the JUPITER Trial

Abstract 13310: Anti-Inflammatory HDL Function and Incident Cardiovascular/Death Events: A Secondary Analysis of the JUPITER Trial

BackgroundHDL cholesterol (HDLC) is an established marker of cardiovascular risk that possesses anti-inflammatory properties in vitro. It is unclear whether the anti-inflammatory quality of HDL in patients treated with statin therapy may be protective against clinical events.MethodsWe measured the f...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A13310-A13310
Hauptverfasser: Ajala, Oluremi N, Demler, Olga, Farukhi, Zareen, Liu, Yanyan, Adelman, Steven, Collins, Heidi, Glynn, Robert, Ridker, Paul, Khera, Amit, Rader, Dan, Mora, Samia
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Sprache:eng
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Zusammenfassung:BackgroundHDL cholesterol (HDLC) is an established marker of cardiovascular risk that possesses anti-inflammatory properties in vitro. It is unclear whether the anti-inflammatory quality of HDL in patients treated with statin therapy may be protective against clinical events.MethodsWe measured the functional ability of HDL to inhibit oxidation of LDL, i.e. HDL inflammatory index (HII, with a ratio
ISSN:0009-7322
1524-4539