Abstract 12264: Mean Left Atrial Pressure Predicts Recurrence of Atrial Fibrillation After Endocardial Ablation: Results From a Single-Centre Prospective Cohort

IntroductionCatheter ablation is a mainstay of atrial fibrillation (AF) treatment. Certain risk factors for recurrence of AF have been identified, allowing tailored medical therapy and follow-up.HypothesisWe aimed to evaluate the impact of mean left atrial pressure (mLAP), measured at the start of the AF ablation procedure, on the rate of AF recurrence at 1 year.MethodsWe performed a prospective, single-centre cohort of patients undergoing ablation of paroxysmal or persistent AF in a university hospital between May 2015 and March 2016. Patients were treated by radiofrequency or cryoablation. mLAP was measured immediately after transseptal puncture. Patients were followed-up at 3 months and 1 year, with a 12-lead ECG and 24h holter ECG monitoring. Medical therapy post-procedure was at the physician’s discretion. Recurrence of AF was defined as at least one ECG- or Holter-documented episode of AF, atrial tachycardia or flutter lasting at least 30 seconds.Results109 patients were included, mean age 61±9.5 years; 68% had paroxysmal and 32% persistent AF. For 93%, it was their first procedure. The recurrence rate at 1 year was 22.9%. Patients with recurrent AF at 1 year had significantly higher mLAP than those without recurrence (14.3±1.17 mmHg vs 6.67±0.46 mmHg ; p2 years vs