Abstract 10655: Energy Drink Induced Impairment of Arterial Endothelial Function in Healthy Young Adults

IntroductionConsumption of energy drinks have been associated with adverse events on the cardiovascular, neurological, gastrointestinal, renal, endocrine, and psychiatric systems, especially in those of young age, small stature, caffeine-naïve/sensitive, pregnant/breastfeeding women, those with cert...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A10655-A10655
Hauptverfasser: Higgins, John P, Jacob, Robin, Husain, Farzan, Liras, Ioannis N, Liras, George N, Ortiz, Brandon L, Bhatti, Karan, Yang, Benjamin, Le, George T
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Sprache:eng
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Zusammenfassung:IntroductionConsumption of energy drinks have been associated with adverse events on the cardiovascular, neurological, gastrointestinal, renal, endocrine, and psychiatric systems, especially in those of young age, small stature, caffeine-naïve/sensitive, pregnant/breastfeeding women, those with certain medical conditions and/or taking certain medications, consuming multiple energy drinks in one session, and those with underlying medical conditions. Cardiovascular side effects associated with energy drink consumption may be related to effects on vascular endothelial function. Thus, we studied the effect of energy drink consumption on endothelial function.HypothesisConsumption of energy drinks acutely leads to impairment of endothelial function in young healthy adults.MethodsForty-four healthy non-smoking young medical students, average age of 24.7 years (range 23-27 years), average BMI 23.4, received a blood pressure & pulse check, and an electrocardiogram. Subjects then underwent baseline testing of endothelial function using the technique of endothelium-dependent flow-mediated dilatation (FMD) with high-resolution ultrasound. The subjects then drank an energy drink [24-oz Monster Energy Drink®], and measurements repeated at 90 min later. The FMD was calculated as the ratio of the post-cuff release and the baseline diameter.ResultsEnergy drink consumption resulted in a significantly attenuated peak FMD response (mean+/-SD)baseline 5.1+/-4.1% vs. post-energy drink 2.8+/-3.8%; p=0.004).ConclusionsEnergy drink consumption was associated with an acute significant impairment in endothelial function in young healthy adults. As energy drinks are becoming more and more popular, it is important to study the effects of these drinks on those who frequently drink them and better determine what if any is a safe consumption pattern.
ISSN:0009-7322
1524-4539