Abstract 20072: Prognostic Value of Baseline Right Ventricular Dysfunction in Patients Undergoing Transcatheter Aortic Valve Replacement

IntroductionThe prevalence of right ventricular dysfunction (RVD) and its relationship with all-cause mortality in severe aortic stenosis patients treated with transcatheter aortic valve replacement (TAVR) is unknown.HypothesisPresence of baseline RVD in patients treated with TAVR is associated with increased all-cause mortality.MethodsWe assessed RV function in 237 patients who underwent TAVR from July 2011 through July 2015. Tricuspid annular plane systolic excursion (TAPSE) was measured in the apical 4-chamber view. RVD is defined as TAPSE 40 clinical parameters and risk factors, was calculated. Notably, the STS-PROM score does not account for RVD. Kaplan-Meier curves and Cox models were used to quantify the effect of RVD on mortality; the Akaike Information Criterion (AIC) was used to select the TAPSE threshold most strongly associated with all-cause mortality.ResultsPatients had median age 84 years, 50% were male, and had predominantly NYHA class ≥ III symptoms (72%) at presentation. Mean STS-PROM was 9.5 ± 5.1%, LVEF 52±14% and RV TAPSE were 17 ± 5mm. By AIC, TAPSE