A "Good Parent" Function of Dopamine

:  While extracellular dopamine (DA) concentrations are increased by a wide category of salient stimuli, there is evidence to suggest that DA responses to primary and conditioned rewards may be distinct from those elicited by other types of salient events. A reward‐specific mode of neuronal respondi...

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Veröffentlicht in:Annals of the New York Academy of Sciences 2007-05, Vol.1104 (1), p.270-288
Hauptverfasser: HORVITZ, JON C., CHOI, WON YUNG, MORVAN, CECILE, EYNY, YANIV, BALSAM, PETER D.
Format: Artikel
Sprache:eng
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Zusammenfassung::  While extracellular dopamine (DA) concentrations are increased by a wide category of salient stimuli, there is evidence to suggest that DA responses to primary and conditioned rewards may be distinct from those elicited by other types of salient events. A reward‐specific mode of neuronal responding would be necessary if DA acts to strengthen behavioral response tendencies under particular environmental conditions or to set current environmental inputs as goals that direct approach responses. As described in this review, DA critically mediates both the acquisition and expression of learned behaviors during early stages of training, however, during later stages, at least some forms of learned behavior become independent of (or less dependent upon) DA transmission for their expression.
ISSN:0077-8923
1749-6632
DOI:10.1196/annals.1390.017