DermaTOP Blue and Antera 3D as methods to assess cosmetic solutions targeting eyelid sagging

Background As the eye contour ages, the skin on the lid becomes lax often causing a voluminous protrusion where the superior palpebral sulcus begins to sag onto the upper eyelid. This sagging feature may present a novel anti‐ageing target for cosmetic products when treating the eye area. A quantitative method to evaluate the volume of this sagging feature has not been previously established. We investigate the use of the DermaTOP fringe projector and Antera 3D Camera to this end. Methods Eyelid topographic measurements were collected on 20 female volunteers aged 50‐75 years with the DermaTOP and Antera 3D. The DermaTOP and Antera 3D measurements were assessed for reproducibility and product effect detection capabilities. Results The DermaTOP and Antera 3D successfully measured sagging feature volume, demonstrated reproducibility of measurement and furthermore were suitably sensitive to allow for detection of sagging feature volume reduction after a single application of aqueous tightening serum. DermaTOP parameters were found to moderately correlated with the Antera 3D parameters. Conclusion Both the DermaTOP and Antera 3D allow for quantitative measurement of eyelid sagging feature volume and in‐turn permit evaluation of anti‐ageing cosmetic preparations targeting the eyelid.