Eligibility for sacubitril/valsartan in heart failure across the ejection fraction spectrum: real‐world data from the Swedish Heart Failure Registry

Background Randomized controlled trials (RCT) generalizability may be limited due to strict patient selection. Objective In a real‐world heart failure (HF) population, we assessed eligibility for sacubitril/valsartan based on PARADIGM‐HF (sacubitril/valsartan effective)/PARAGON‐HF [sacubitril/valsar...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of internal medicine 2021-03, Vol.289 (3), p.369-384
Hauptverfasser: Savarese, G., Hage, C., Benson, L., Schrage, B., Thorvaldsen, T., Lundberg, A., Fudim, M., Linde, C., Dahlström, U., Rosano, G. M. C., Lund, L. H.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Background Randomized controlled trials (RCT) generalizability may be limited due to strict patient selection. Objective In a real‐world heart failure (HF) population, we assessed eligibility for sacubitril/valsartan based on PARADIGM‐HF (sacubitril/valsartan effective)/PARAGON‐HF [sacubitril/valsartan effective in mildly reduced ejection fraction (EF)]. Methods Outpatients from the Swedish HF Registry (SwedeHF) were analysed. In SwedeHF, EF is recorded as
ISSN:0954-6820
1365-2796
1365-2796
DOI:10.1111/joim.13165