Hypogammaglobulinemia following heart transplantation: Prevalence, predictors, and clinical importance

Hypogammaglobulinemia following heart transplantation: Prevalence, predictors, and clinical importance

Hypogammaglobulinemia (HGG) can occur following solid organ transplantation. However, there are limited data describing the prevalence, risk factors, and clinical outcomes associated with HGG following heart transplantation. We retrospectively reviewed data of 132 patients who had undergone heart tr...

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Veröffentlicht in:Clinical transplantation 2020-12, Vol.34 (12), p.e14087-n/a, Article 14087
Hauptverfasser: Fujino, Takeo, Kumai, Yuto, Nitta, Daisuke, Holzhauser, Luise, Nguyen, Ann, Lourenco, Laura, Rodgers, Daniel, Raikhelkar, Jayant, Kim, Gene, Sayer, Gabriel, Uriel, Nir
Format: Artikel
Sprache:eng
Schlagworte:
Agammaglobulinemia - epidemiology
Agammaglobulinemia - etiology
Female
heart transplantation
Heart Transplantation - adverse effects
Humans
hypogammaglobulinemia
Immunoglobulin G
infection
Life Sciences & Biomedicine
Male
Middle Aged
outcome
Prevalence
Retrospective Studies
Risk Factors
Science & Technology
Surgery
Transplantation
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Zusammenfassung:Hypogammaglobulinemia (HGG) can occur following solid organ transplantation. However, there are limited data describing the prevalence, risk factors, and clinical outcomes associated with HGG following heart transplantation. We retrospectively reviewed data of 132 patients who had undergone heart transplantation at our institution between April 2014 and December 2018. We classified patients into three groups based on the lowest serum IgG level post‐transplant: normal (≥700 mg/dL), mild HGG (≥450 and
ISSN:0902-0063
1399-0012
DOI:10.1111/ctr.14087