A Study Of the Effect of Some Emulsifying Agents on Drug Release from Suppository Bases
Suppositories consisting of varying amounts of hydrogenated cottonseed oil, Tweens, Sans, and Arlacels were incorporated with a dye and tested for the percentage of dye release at time intervals. Most of the suppositories were tested for storage qualities and seven were subjected to in vivo tests. S...
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Veröffentlicht in: | Journal of the American Pharmaceutical Association (Scientific ed.) 1959-06, Vol.48 (6), p.353-355 |
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container_title | Journal of the American Pharmaceutical Association (Scientific ed.) |
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creator | Whitworth, Clyde W. Larocca, Joseph P. |
description | Suppositories consisting of varying amounts of hydrogenated cottonseed oil, Tweens, Sans, and Arlacels were incorporated with a dye and tested for the percentage of dye release at time intervals. Most of the suppositories were tested for storage qualities and seven were subjected to in vivo tests. Several of the proposed bases appear to be very promising and compare favorably in vivo with a commercial brand of suppository now being widely used. |
doi_str_mv | 10.1002/jps.3030480615 |
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Most of the suppositories were tested for storage qualities and seven were subjected to in vivo tests. Several of the proposed bases appear to be very promising and compare favorably in vivo with a commercial brand of suppository now being widely used.</description><identifier>ISSN: 0095-9553</identifier><identifier>EISSN: 1930-2304</identifier><identifier>DOI: 10.1002/jps.3030480615</identifier><identifier>PMID: 13654093</identifier><language>eng</language><publisher>Washington, D. 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Pharm. Sci</addtitle><description>Suppositories consisting of varying amounts of hydrogenated cottonseed oil, Tweens, Sans, and Arlacels were incorporated with a dye and tested for the percentage of dye release at time intervals. Most of the suppositories were tested for storage qualities and seven were subjected to in vivo tests. 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Pharm. Sci</addtitle><date>1959-06</date><risdate>1959</risdate><volume>48</volume><issue>6</issue><spage>353</spage><epage>355</epage><pages>353-355</pages><issn>0095-9553</issn><eissn>1930-2304</eissn><abstract>Suppositories consisting of varying amounts of hydrogenated cottonseed oil, Tweens, Sans, and Arlacels were incorporated with a dye and tested for the percentage of dye release at time intervals. Most of the suppositories were tested for storage qualities and seven were subjected to in vivo tests. Several of the proposed bases appear to be very promising and compare favorably in vivo with a commercial brand of suppository now being widely used.</abstract><cop>Washington, D. C</cop><pub>Elsevier Inc</pub><pmid>13654093</pmid><doi>10.1002/jps.3030480615</doi><tpages>3</tpages></addata></record> |
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issn | 0095-9553 1930-2304 |
language | eng |
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source | MEDLINE; Alma/SFX Local Collection |
subjects | Drug Liberation Emulsifying Agents Emulsions Pharmaceutical Preparations Polyethylene Glycols Suppositories |
title | A Study Of the Effect of Some Emulsifying Agents on Drug Release from Suppository Bases |
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