16α-Hydroxy Steroids I : Characterization of Triamcinolone

Triamcinolone and triamcinolone 16α,21-diacetate have been characterized by ultraviolet absorption spectra, infrared absorption spectra, absorption spectra in sulfuric acid, polarography, reduction of tetrazolium blue, and by Porter-Silber chromogens. The use of absorption spectra, polarography, and...

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Veröffentlicht in:Journal of the American Pharmaceutical Association (Scientific ed.) 1959-06, Vol.48 (6), p.348-352
Hauptverfasser: Smith, Leland L., Halwer, Murray
Format: Artikel
Sprache:eng
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Zusammenfassung:Triamcinolone and triamcinolone 16α,21-diacetate have been characterized by ultraviolet absorption spectra, infrared absorption spectra, absorption spectra in sulfuric acid, polarography, reduction of tetrazolium blue, and by Porter-Silber chromogens. The use of absorption spectra, polarography, and colorimetry for quantitative determination of bulk triamcinolone and of triamcinolone in tablets is discussed. Some new chemistry of 16α-hydroxylated steroids is reviewed.
ISSN:0095-9553
1930-2304
DOI:10.1002/jps.3030480614