An Evaluation of Certain Hypotensive Agents II : Acetylenic Bis-Onium Derivatives

A series of nine new bis-quaternary and three bis-tertiary ammonium compounds were screened and evaluated for their hypotensive activity in rats. Further studies were conducted on dogs. It was found that there was a definite qualitative correlation between the responses in rats and dogs. Pentolinium...

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Veröffentlicht in:Journal of the American Pharmaceutical Association (Scientific ed.) 1957-10, Vol.46 (10), p.598-601
Hauptverfasser: Schalit, F.M., Buckley, J.P., Hudak, W.J., DeFeo, J.J., Reif, E.C.
Format: Artikel
Sprache:eng
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