Zn(OAc)2•2H2O‐catalyzed synthesis of α‐aminophosphonates under neat reaction
A series of novel α‐aminophosphonates have been prepared by one‐pot three‐component condensation in the presence of a zinc acetate (Zn(OAc)2•2H2O) catalyst at 50°C under solvent‐free conditions with excellent yields. The major advantages of the present method are high yields, a short reaction time,...
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| Veröffentlicht in: | Heteroatom chemistry 2012, Vol.23 (2), p.160-165 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | A series of novel α‐aminophosphonates have been prepared by one‐pot three‐component condensation in the presence of a zinc acetate (Zn(OAc)2•2H2O) catalyst at 50°C under solvent‐free conditions with excellent yields. The major advantages of the present method are high yields, a short reaction time, and solvent‐free reaction conditions. Their antimicrobial activity was evaluated, and some of them showed significant activity. © 2011 Wiley Periodicals, Inc. Heteroatom Chem 23:160–165, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20765 |
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| ISSN: | 1042-7163 1098-1071 |
| DOI: | 10.1002/hc.20765 |