Nodal yield and survival in oral squamous cancer

Nodal yield and survival in oral squamous cancer

BACKGROUND: Elective neck dissection (END) is commonly used as a staging and therapeutic procedure for oral squamous cell carcinoma (SCC) at high risk of nodal metastases. The authors aimed to determine whether the extent of lymphadenectomy, as defined by nodal yield, is a prognostic factor in this...

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Veröffentlicht in:Cancer 2011-07, Vol.117 (13), p.2917-2925
Hauptverfasser: Ebrahimi, Ardalan, Zhang, Wan J., Gao, Kan, Clark, Jonathan R.
Format: Artikel
Sprache:eng
Schlagworte:
head and neck
lymph nodes
neck dissection
oral cavity
squamous cell carcinoma
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Zusammenfassung:BACKGROUND: Elective neck dissection (END) is commonly used as a staging and therapeutic procedure for oral squamous cell carcinoma (SCC) at high risk of nodal metastases. The authors aimed to determine whether the extent of lymphadenectomy, as defined by nodal yield, is a prognostic factor in this setting. METHODS: A retrospective database review identified 225 patients undergoing END with curative intent for oral SCC between 1987 and 2009. Nodal yield was studied as a categorical variable for association with overall, disease‐specific, and disease‐free survival in univariate and multivariate analyses. RESULTS: Nodal yield
ISSN:0008-543X
1097-0142
DOI:10.1002/cncr.25834