Discovery of Brivanib Alaninate: A Dual Vascular Endothelial Growth Factor and Fibroblast Growth Factor Receptor Inhibitor

Discovery of Brivanib Alaninate: A Dual Vascular Endothelial Growth Factor and Fibroblast Growth Factor Receptor Inhibitor

This chapter contains sections titled: Introduction VEGFR and FGFR as Angiogenesis Targets Discovery of Brivanib Alaninate: Preclinical Studies Clinical Studies Potential Liabilities of Antiangiogenic Therapy Conclusions and Future Directions Appendix: Formula for Calculation of Tumor Growth Inhibit...

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Hauptverfasser: Bhide, Rajeev S, Fargnoli, Joseph
Format: Buchkapitel
Sprache:eng
Schlagworte:
brivanib alaninate discovery
dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI)
VEGFR2 kinase domain
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Zusammenfassung:This chapter contains sections titled: Introduction VEGFR and FGFR as Angiogenesis Targets Discovery of Brivanib Alaninate: Preclinical Studies Clinical Studies Potential Liabilities of Antiangiogenic Therapy Conclusions and Future Directions Appendix: Formula for Calculation of Tumor Growth Inhibition Acknowledgment References
DOI:10.1002/9780470524961.ch6