In vivo imaging reveals increased eosinophil uptake in the lungs of obese asthmatic patients

Using radiolabeled eosinophils coupled with SPECT/CT the authors quantify eosinophilic inflammation in the lungs of patients with asthma and focal pulmonary eosinophilic inflammation, revealing important differences in eosinophil kinetics between obese and non-obese asthmatics.

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Hauptverfasser: Farahi, N, Loutsios, C, Tregay, N, Wright, A.K.A, Berair, R, Lok, L.S.C, Gillett, D, Cullum, I, Simmonds, R.P, Summers, C, Wong, A, Solanki, C.K, Buscombe, J, Pang, P.H, Thavakumar, A, Peters, A.M, Brightling, C.E, Condliffe, A.M, Chilvers, E.R
Format: Artikel
Sprache:eng
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Zusammenfassung:Using radiolabeled eosinophils coupled with SPECT/CT the authors quantify eosinophilic inflammation in the lungs of patients with asthma and focal pulmonary eosinophilic inflammation, revealing important differences in eosinophil kinetics between obese and non-obese asthmatics.
DOI:10.1016/j.jaci.2018.07.011