Transfer of Radiobismuth to the Fetus in Guinea-Pigs

A survey of the literature regarding the biomedical properties of inhaled short-lived decay products of radon showed that the importance of the physical, biochemical and biokinetic properties of bismuth radionuclides have been greatly overlooked, especially in the prenatal and preconception stages o...

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Veröffentlicht in:Radiation Protection Dosimetry [RADIAT. PROT. DOSIMET.]. Vol. 41, no. 2-4. 1992 no. 2-4. 1992, 1992-01, Vol.41 (2-4), p.169-172
1. Verfasser: RICHARDSON, RB
Format: Artikel
Sprache:eng
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Zusammenfassung:A survey of the literature regarding the biomedical properties of inhaled short-lived decay products of radon showed that the importance of the physical, biochemical and biokinetic properties of bismuth radionuclides have been greatly overlooked, especially in the prenatal and preconception stages of human development. As no data are available on the placental uptake of bismuth, a small animal study was carried out in guinea-pigs to measure uptake of radiobismuth in fetal organs after intravenous administration to the mother. In this study, little activity was found to cross the placental barrier with
ISSN:0144-8420
1742-3406
DOI:10.1093/oxfordjournals.rpd.a081251