Inclusion body myositis: its relative frequency in elderly people

Inclusion body myositis (IBM) is a distinct, steroid resistant, form of inflammatory myopathy. Its recognition is the more important because of the preponderant occurrence in the elderly, in whom steroid treatment is hazardous. Since the relative frequency of IBM among inflammatory myopathies in the...

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Veröffentlicht in:	Clinical neurology and neurosurgery 1992, Vol.94, p.118-120
Hauptverfasser:	Maat-Schieman, M.L.C., Macfarlane, J.D., Bots, G.T.A.M., Wintzen, A.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Biopsy Clinical Neurology Diseases of striated muscles. Neuromuscular diseases Elderly people Female Humans Inclusion Bodies - ultrastructure Inclusion body myositis Inflammatory myopathy Life Sciences & Biomedicine Male Medical sciences Microscopy, Electron Middle Aged Muscles - pathology Myositis - pathology Neurology Neurosciences & Neurology Science & Technology Surgery
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Zusammenfassung:	Inclusion body myositis (IBM) is a distinct, steroid resistant, form of inflammatory myopathy. Its recognition is the more important because of the preponderant occurrence in the elderly, in whom steroid treatment is hazardous. Since the relative frequency of IBM among inflammatory myopathies in the elderly is undetermined, we retrospectively studied its frequency among all our patients over 50 years, diagnosed between 1980 and 1991 with inflammatory myopathy. Nine of 15 patients with inflammatory myopathy appeared to suffer from IBM. In a further 2 patients this diagnosis was strongly suspected. We conclude that IBM is the most frequent inflammatory myopathy in the elderly. This observation warrants restraint with steroids in the management of inflammatory myopathy in the elderly.
ISSN:	0303-8467 1872-6968
DOI:	10.1016/0303-8467(92)90043-3