Risk factors for microbiologic failure in children with Enterobacter species bacteremia

Background Enterobacter species are an important cause of healthcare-associated bloodstream infections (BSI) in children. Up to 19% of adult patients with Enterobacter BSI have recurrence of infection resistant to third-generation cephalosporins (3GCs) while on therapy with a 3GC. Data are lacking r...

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Veröffentlicht in:	PloS one 2021-10, Vol.16 (10), p.e0258114-e0258114, Article 0258114
Hauptverfasser:	Boguniewicz, Juri, Revell, Paula A., Scheurer, Michael E., Hulten, Kristina G., Palazzi, Debra L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abscesses Adequacy Antibiotics Bacteremia Biology and Life Sciences Catheters Cephalosporins Children Demographic aspects Disease susceptibility Diseases Enterobacter Enterobacteriaceae Evaluation Failure Health aspects Health risks Hospitals Infections Infectious diseases Intensive care Laboratories Medical schools Medicine Medicine and Health Sciences Mortality Multidisciplinary Sciences Patients Pediatrics Risk analysis Risk factors Science & Technology Science & Technology - Other Topics Urinary tract
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Zusammenfassung:	Background Enterobacter species are an important cause of healthcare-associated bloodstream infections (BSI) in children. Up to 19% of adult patients with Enterobacter BSI have recurrence of infection resistant to third-generation cephalosporins (3GCs) while on therapy with a 3GC. Data are lacking regarding the incidence of and risk factors for recurrence of infection in children with Enterobacter BSI. Methods We conducted a retrospective case-control study of patients aged
ISSN:	1932-6203 1932-6203
DOI:	10.1371/journal.pone.0258114