Impact of sarcopenia on prognosis in patients with heart failure with reduced and preserved ejection fraction

Impact of sarcopenia on prognosis in patients with heart failure with reduced and preserved ejection fraction

Aims Sarcopenia, one of the extracardiac factors for reduced functional capacity and poor outcome in heart failure (HF), may act differently between HF with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF). We sought to investigate the impact of sarcopenia on mortali...

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Veröffentlicht in:European journal of preventive cardiology 2021-08, Vol.28 (9), p.1022-1029
Hauptverfasser: Konishi, Masaaki, Kagiyama, Nobuyuki, Kamiya, Kentaro, Saito, Hiroshi, Saito, Kazuya, Ogasahara, Yuki, Maekawa, Emi, Misumi, Toshihiro, Kitai, Takeshi, Iwata, Kentaro, Jujo, Kentaro, Wada, Hiroshi, Kasai, Takatoshi, Nagamatsu, Hirofumi, Ozawa, Tetsuya, Izawa, Katsuya, Yamamoto, Shuhei, Aizawa, Naoki, Makino, Akihiro, Oka, Kazuhiro, Momomura, Shin-Ichi, Matsue, Yuya
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Cardiac & Cardiovascular Systems
Cardiovascular System & Cardiology
Female
Hand Strength
Heart Failure
Humans
Life Sciences & Biomedicine
Male
Prognosis
Prospective Studies
Risk Factors
Sarcopenia - diagnosis
Sarcopenia - epidemiology
Science & Technology
Stroke Volume - physiology
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Zusammenfassung:Aims Sarcopenia, one of the extracardiac factors for reduced functional capacity and poor outcome in heart failure (HF), may act differently between HF with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF). We sought to investigate the impact of sarcopenia on mortality in HFpEF and HFrEF. Methods and results We performed a post hoc analysis of a multicentre prospective cohort study, including 942 consecutive older (age >= 65 years) hospitalized patients: 475 with HFpEF (ejection fraction >= 45%, age 817 years, 48.8% men) and 467 with HFrEF (ejection fraction
ISSN:2047-4873
2047-4881
DOI:10.1093/eurjpc/zwaa117