Reduction of Visceral Adiposity as a Predictor for Resolution of Nonalcoholic Fatty Liver in Potential Living Liver Donors

Reduction of Visceral Adiposity as a Predictor for Resolution of Nonalcoholic Fatty Liver in Potential Living Liver Donors

This study aimed to determine the factors associated with resolution of nonalcoholic fatty liver (NAFL) after lifestyle intervention in potential living liver donors as assessed by the gold standards in a longitudinal setting. This retrospective study included 115 potential living liver donors (mean...

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Veröffentlicht in:Liver transplantation 2021-10, Vol.27 (10), p.1424-1431
Hauptverfasser: Lee, Sunyoung, Kim, Kyoung Won, Lee, Jeongjin, Park, Taeyong, Park, Hyo Jung, Song, Gi‐Won, Lee, Sung‐Gyu
Format: Artikel
Sprache:eng
Schlagworte:
Adipose tissue
Adiposity
Adult
Anthropometry
Biopsy
Body composition
Body Mass Index
Body weight
Computed tomography
Fatty liver
Gastroenterology & Hepatology
Humans
Laboratories
Life Sciences & Biomedicine
Lifestyles
Liver
Liver Transplantation
Male
Non-alcoholic Fatty Liver Disease - diagnostic imaging
Non-alcoholic Fatty Liver Disease - therapy
Organ donors
Retrospective Studies
Science & Technology
Skeletal muscle
Steatosis
Surgery
Transplantation
Young Adult
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Zusammenfassung:This study aimed to determine the factors associated with resolution of nonalcoholic fatty liver (NAFL) after lifestyle intervention in potential living liver donors as assessed by the gold standards in a longitudinal setting. This retrospective study included 115 potential living liver donors (mean age, 30.5 ± 7.5 years; 101 men) with NAFL who underwent paired liver biopsies and abdominal computed tomography (CT) examinations before and after lifestyle intervention between January 2011 and December 2018. Anthropometry, laboratory parameters, body composition, and hepatic steatosis (HS) were evaluated before and after lifestyle intervention. Anthropometry, laboratory parameters, body composition, and HS were significantly decreased after lifestyle intervention (all, P 
ISSN:1527-6465
1527-6473
DOI:10.1002/lt.26071