Long‐term risk of end‐stage renal diseases with maintenance dialysis among chronic hepatitis C patients after antiviral therapy in Taiwan

Background and Aim Chronic hepatitis C virus (HCV) infection is associated with impaired renal function. The aim of this study is to explore the risk of and factors associated with end‐stage renal diseases (ESRD) under maintenance dialysis among HCV patients after anti‐HCV therapy. Methods A total o...

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Veröffentlicht in:Journal of gastroenterology and hepatology 2021-08, Vol.36 (8), p.2247-2254
Hauptverfasser: Hsieh, Meng‐Hsuan, Bair, Ming‐Jong, Tsai, Pei‐Chien, Tseng, Kuo‐Chih, Lo, Ching‐Chu, Chen, Chi‐Yi, Kuo, Hsing‐Tao, Hung, Chao‐Hung, Lai, Hsueh‐Chou, Peng, Cheng‐Yuan, Wang, Jing‐Houng, Chen, Jyh‐Jou, Lee, Pei‐Lun, Chien, Rong‐Nan, Yang, Chi‐Chieh, Lo, Gin‐Ho, Kao, Jia‐Horng, Liu, Chun‐Jen, Liu, Chen‐Hua, Yan, Sheng‐Lei, Lin, Chun‐Yen, Su, Wei‐Wen, Chu, Cheng‐Hsin, Chen, Chih‐Jen, Tung, Shui‐Yi, Tai, Chi‐Ming, Lin, Chih‐Wen, Cheng, Pin‐Nan, Chiu, Yen‐Cheng, Wang, Chia‐Chi, Cheng, Jin‐Shiung, Tsai, Wei‐Lun, Lin, Han‐Chieh, Huang, Yi‐Hsiang, Yeh, Ming‐Lun, Huang, Chung‐Feng, Huang, Jee‐Fu, Dai, Chia‐Yen, Yu, Ming‐Lung, Chuang, Wan‐Long
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Sprache:eng
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Zusammenfassung:Background and Aim Chronic hepatitis C virus (HCV) infection is associated with impaired renal function. The aim of this study is to explore the risk of and factors associated with end‐stage renal diseases (ESRD) under maintenance dialysis among HCV patients after anti‐HCV therapy. Methods A total of 12 696 HCV‐infected patients with interferon‐based therapy, including 9679 (76.2%) achieving sustained virological response (SVR), were enrolled from 23 hospitals in Taiwan. Results During a mean follow‐up period of 5.3 years (67 554 person‐years), the annual incidence of 4.1/10 000 person‐years, 4.0/10 000 and 4.7/10 000 person‐years among SVR patients and non‐SVR patients, respectively. History of diabetes and baseline estimated glomerular filtration rate 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.15469