Daily computed tomography image guidance: Dosimetric advantages outweigh low-dose radiation exposure for treatment of mediastinal lymphoma

CT-guided treatment delivery can improve target localization in mediastinal lymphoma patients treated with “butterfly” intensity-modulated radiotherapy and deep-inspiration breath hold. Although daily CT imaging adds additional radiation exposure, its use may be justified given the greater normal ti...

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Veröffentlicht in:	Radiotherapy and oncology 2020-11, Vol.152, p.14-18
Hauptverfasser:	Zhu, Lin L., Martin, Rachael M., Gunther, Jillian R., Wong, Pei-Fong, Hancock, Donald, Moreno, Amy C., Dabaja, Bouthaina S., Pinnix, Chelsea C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Computed tomography image guided radiation therapy Dosimetry Humans Intensity-modulated radiotherapy Life Sciences & Biomedicine Lymphoma - diagnostic imaging Lymphoma - radiotherapy Mediastinal lymphoma Oncology Radiation Exposure Radiology, Nuclear Medicine & Medical Imaging Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted Radiotherapy, Intensity-Modulated Science & Technology Tomography, X-Ray Computed
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Zusammenfassung:	CT-guided treatment delivery can improve target localization in mediastinal lymphoma patients treated with “butterfly” intensity-modulated radiotherapy and deep-inspiration breath hold. Although daily CT imaging adds additional radiation exposure, its use may be justified given the greater normal tissue sparing enabled by PTV margin reduction.
ISSN:	0167-8140 1879-0887
DOI:	10.1016/j.radonc.2020.06.028