Immunotherapeutic strategies in breast cancer: A clinical update

Immunotherapy has been incorporated into the standard of care for a wide range of malignancies. The study of tumor‐infiltrating lymphocytes has emphasized the importance of the host antitumor immune response in the natural history of breast cancer. Recent clinical trials have used immunotherapeutic...

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Veröffentlicht in:Journal of surgical oncology 2021-03, Vol.123 (3), p.710-717
Hauptverfasser: Zhang, Jennifer Q., Plitas, George
Format: Artikel
Sprache:eng
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Zusammenfassung:Immunotherapy has been incorporated into the standard of care for a wide range of malignancies. The study of tumor‐infiltrating lymphocytes has emphasized the importance of the host antitumor immune response in the natural history of breast cancer. Recent clinical trials have used immunotherapeutic approaches to augment this response and improve outcomes for patients with breast cancer. Here, we review several current clinical trial data that indicate checkpoint blockade may mediate clinically significant responses.
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.26287